Design and Development of Graphene-Based C-Shaped Silicon-MgF2-Silicon Materials Surface Plasmon Resonance Biosensor for Cervical Cancer Detection

IF 4.3 4区物理与天体物理 Q2 CHEMISTRY, PHYSICAL

Plasmonics Pub Date : 2025-04-14 DOI:10.1007/s11468-025-02958-w

Gokila Dhandapani, Porchelvi N, Arun Kumar U, Fahad Ahmed Al-Zahrani

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引用次数: 0

Abstract

A cervical biosensor is a diagnostic tool designed to detect biomarkers associated with cervical cancer. It provides early, non-invasive, and highly sensitive detection, aiding in timely diagnosis and improving patient outcomes. A high-sensitivity sensor is ideal for the early detection of cervical cancer, as it can detect low levels of biomarkers associated with the disease. Early detection improves the chances of successful treatment, allowing for timely intervention and better patient outcomes. This makes high-sensitivity sensors crucial in developing more effective, non-invasive diagnostic tools for cervical cancer. Our sensor demonstrates a high sensitivity of 1208 nm/RIU, enabling precise and early detection of cervical cancer biomarkers for improved diagnosis. Structural optimization enhances the sensor’s sensitivity by adjusting key parameters such as length, width, and height, ensuring improved performance and more accurate detection capabilities for cervical cancer biomarkers. The high-sensitivity sensor developed in this research can be utilized to create advanced devices for the early detection of cervical cancer, offering improved diagnostic accuracy and efficiency.

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基于石墨烯的c型硅- mgf2 -硅材料表面等离子体共振生物传感器的设计与研制

宫颈生物传感器是一种诊断工具，用于检测与宫颈癌相关的生物标志物。它提供了早期、非侵入性和高度敏感的检测，有助于及时诊断和改善患者的预后。高灵敏度传感器是宫颈癌早期检测的理想选择，因为它可以检测到与该疾病相关的低水平生物标志物。早期发现提高了成功治疗的机会，允许及时干预和更好的患者预后。这使得高灵敏度传感器在开发更有效、非侵入性的宫颈癌诊断工具方面至关重要。我们的传感器具有1208 nm/RIU的高灵敏度，能够精确和早期检测宫颈癌生物标志物，从而提高诊断水平。结构优化通过调整传感器的长度、宽度和高度等关键参数，提高了传感器的灵敏度，确保了更好的性能和更准确的宫颈癌生物标志物检测能力。本研究开发的高灵敏度传感器可用于制造先进的宫颈癌早期检测设备，提高诊断的准确性和效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plasmonics 工程技术-材料科学：综合

CiteScore

5.90

自引率

6.70%

发文量

164

审稿时长

2.1 months

期刊介绍： Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.