Fabrication of a microfluidic chip using mechanical micromilling for flocculant testing

IF 2.5 4区 工程技术 Q2 INSTRUMENTS & INSTRUMENTATION
Parvathi K K, Nithin Tom Mathew
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Abstract

The fabrication of microfluidic chips using mechanical micromilling offers a promising method for rapid prototyping. This study investigates the use of mechanical micromilling to produce microchannels in Polymethyl methacrylate for flocculant testing, which requires precision and smooth surfaces to ensure effective fluid flow and mixing. The dimensional accuracy of the fabricated microchannels was evaluated using a coordinate measuring machine, and surface quality was analysed through scanning electron microscopy and confocal microscopy. The coordinate measuring measurements indicated high consistency across most features, but significant deviations were observed in specific regions, suggesting challenges in achieving tight tolerances for certain geometric features. The scanning electron micrographs analysis revealed surface imperfections, including excess burrs and feed marks, which could negatively impact fluid flow in microchannels. Confocal microscopy confirmed the presence of high surface roughness, with pronounced peaks and valleys that could disrupt flow and increase resistance in microfluidic applications. The findings highlight the need to optimise process parameters to improve surface quality. Optimisation of the micromilling parameters and post-processing techniques is necessary to enhance surface quality for the microfluidic device to meet the stringent requirements necessary for effective flocculant testing.

Abstract Image

Abstract Image

用机械微铣削制造絮凝剂测试用微流控芯片
机械微铣削微流控芯片的制造为快速成型提供了一种很有前途的方法。本研究探讨了利用机械微磨在聚甲基丙烯酸甲酯中制造用于絮凝剂测试的微通道,这需要精确和光滑的表面,以确保有效的流体流动和混合。利用三坐标测量机对微通道的尺寸精度进行了评价,并通过扫描电镜和共聚焦显微镜对微通道的表面质量进行了分析。坐标测量结果表明,大多数特征高度一致,但在特定区域观察到明显的偏差,这表明在实现某些几何特征的严格公差方面存在挑战。扫描电子显微图分析显示,表面缺陷,包括多余的毛刺和进料痕迹,可能会对微通道中的流体流动产生负面影响。共聚焦显微镜证实了高表面粗糙度的存在,具有明显的波峰和波谷,可能会破坏流动并增加微流体应用中的阻力。研究结果强调了优化工艺参数以提高表面质量的必要性。优化微磨参数和后处理技术是提高微流控装置表面质量以满足有效絮凝剂测试所必需的严格要求的必要条件。
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来源期刊
Microfluidics and Nanofluidics
Microfluidics and Nanofluidics 工程技术-纳米科技
CiteScore
4.80
自引率
3.60%
发文量
97
审稿时长
2 months
期刊介绍: Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include: 1.000 Fundamental principles of micro- and nanoscale phenomena like, flow, mass transport and reactions 3.000 Theoretical models and numerical simulation with experimental and/or analytical proof 4.000 Novel measurement & characterization technologies 5.000 Devices (actuators and sensors) 6.000 New unit-operations for dedicated microfluidic platforms 7.000 Lab-on-a-Chip applications 8.000 Microfabrication technologies and materials Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).
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