Impact of a laminar air flow portable device on post-intravitreal injection endophthalmitis rate

IF 3.5 2区医学 Q1 OPHTHALMOLOGY

British Journal of Ophthalmology Pub Date : 2025-08-27 DOI:10.1136/bjo-2025-327316

Matteo Airaldi, Salvatore Parrulli, Andrea Trinco, Federico Cinus, Giovanni Staurenghi, Marco Pellegrini, Matteo Cereda

引用次数: 0

Abstract

Intravitreal injections (IVIs) are the most common outpatient procedure worldwide, yet no consensus exists regarding their optimal setting. This study analysed 101 976 IVIs performed between 2017 and 2023, comparing endophthalmitis rates before and after introducing a mobile laminar air flow (LAF) device in a clean room. The incidence of endophthalmitis decreased from 0.033% to 0.013%, a 63.2% risk reduction (Odds Ratio=0.368, p=0.04). These findings suggest that mobile LAF enhances air quality and reduces infection risk, offering a cost-effective, efficient alternative to operating theatres for IVIs.

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层流气流便携式装置对玻璃体内注射后眼内炎发生率的影响

玻璃体内注射（IVIs）是世界范围内最常见的门诊手术，但对其最佳设置尚无共识。本研究分析了2017年至2023年间进行的101 976例静脉注射，比较了在洁净室引入移动层流（LAF）设备前后的眼内炎发生率。眼内炎的发生率从0.033%降至0.013%，风险降低63.2%（优势比=0.368,p=0.04）。这些发现表明，移动LAF提高了空气质量，降低了感染风险，为静脉注射提供了一种成本效益高、效率高的替代方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

British Journal of Ophthalmology 医学-眼科学

CiteScore

10.30

自引率

2.40%

发文量

213

审稿时长

3-6 weeks

期刊介绍： The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. It also provides major reviews and also publishes manuscripts covering regional issues in a global context.