Enhancing medication adherence, depression, and values-based behaviors in HIV-positive individuals through acceptance and commitment therapy: A pilot study

IF 3 3区心理学 Q1 PSYCHOLOGY, CLINICAL

Journal of Contextual Behavioral Science Pub Date : 2025-07-01 DOI:10.1016/j.jcbs.2025.100921

Mariana Téllez , Yors García

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Abstract

This pilot study evaluated the impact of the Acceptance and Commitment Therapy (ACT) matrix on values-driven behaviors, medication adherence, viral load, and depression among individuals living with HIV in a middle-income country. A randomized, non-concurrent multiple baseline design across four participants was employed. Outcomes were assessed at baseline, post-intervention, and follow-up, with daily tracking of values-driven behaviors and medication adherence throughout. Participants underwent a 7-session ACT matrix training. Results revealed increases in values-driven behaviors and improvements in medication adherence across all participants. Viral loads decreased for three participants, with two achieving undetectable levels. Depression scores improved for three participants, with changes sustained through follow-up. Participants described the intervention as acceptable and relevant to addressing adherence barriers and mental health concerns. Findings underscore the potential for ACT to enhance antiretroviral adherence and psychological outcomes in middle-income countries, offering a scalable, culturally adaptable intervention for improving HIV care.

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通过接受和承诺治疗增强hiv阳性个体的药物依从性、抑郁和基于价值观的行为：一项试点研究

本试点研究评估了接受和承诺治疗（ACT）矩阵对中等收入国家艾滋病毒感染者价值观驱动行为、药物依从性、病毒载量和抑郁的影响。在四名参与者中采用随机、非并发多基线设计。结果在基线、干预后和随访中进行评估，并在整个过程中每天跟踪价值观驱动的行为和药物依从性。参与者接受了7期ACT矩阵训练。结果显示，所有参与者的价值观驱动行为有所增加，药物依从性有所改善。三名参与者的病毒载量下降，其中两名达到了检测不到的水平。三名参与者的抑郁得分有所提高，这种变化在随访中持续存在。参与者认为干预措施是可接受的，与解决坚持治疗障碍和心理健康问题相关。研究结果强调了ACT在中等收入国家增强抗逆转录病毒依从性和心理结果的潜力，为改善艾滋病毒护理提供了一种可扩展的、适应文化的干预措施。

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来源期刊

Journal of Contextual Behavioral Science PSYCHOLOGY, CLINICAL-

CiteScore

8.50

自引率

18.00%

发文量

审稿时长

61 days

期刊介绍： The Journal of Contextual Behavioral Science is the official journal of the Association for Contextual Behavioral Science (ACBS). Contextual Behavioral Science is a systematic and pragmatic approach to the understanding of behavior, the solution of human problems, and the promotion of human growth and development. Contextual Behavioral Science uses functional principles and theories to analyze and modify action embedded in its historical and situational context. The goal is to predict and influence behavior, with precision, scope, and depth, across all behavioral domains and all levels of analysis, so as to help create a behavioral science that is more adequate to the challenge of the human condition.