{"title":"A report of the Iranian Parkinson’s disease registry","authors":"Mehri Salari, Masoud Etemadifar, Alireza Vakilian, Ahmad Chitsaz, Kaveh Shafiei, Seyed Masoud Nabavi, Afshin Samaei, Atiye Riasi, Fatemeh Hojjatipour","doi":"10.1038/s41531-025-01108-7","DOIUrl":null,"url":null,"abstract":"<p>Millions of people worldwide suffer from Parkinson’s disease (PD), which has a varying distribution and features in each country. Since there is a shortage of data regarding PD patients in Iran, we present a registry-based study to deepen our understanding of Iranian PD patients’ characteristics, distribution, and clinical differences between genders and different ages of onset. In six years, 4048 patients were interviewed, who had a mean age of 67.66 years, and consisted of 1474 (36.4%) females and 2571 (63.5%) males. Men suffered more from apathy, speech, handwriting, and salivation, while women experienced more anxiety, depression, pain, and psychosis, after multivariable regression. Early-onset Parkinson’s disease (EOPD) and late-onset Parkinson’s disease (LOPD) were divided based on the 50-year-old cut-off age. They were represented by 989 (24.6%) and 2834 (70%) of the total, respectively, and EOPD patients had a higher duration of the disease and a higher positive family history.</p>","PeriodicalId":19706,"journal":{"name":"NPJ Parkinson's Disease","volume":"197 1","pages":""},"PeriodicalIF":8.2000,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"NPJ Parkinson's Disease","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41531-025-01108-7","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Millions of people worldwide suffer from Parkinson’s disease (PD), which has a varying distribution and features in each country. Since there is a shortage of data regarding PD patients in Iran, we present a registry-based study to deepen our understanding of Iranian PD patients’ characteristics, distribution, and clinical differences between genders and different ages of onset. In six years, 4048 patients were interviewed, who had a mean age of 67.66 years, and consisted of 1474 (36.4%) females and 2571 (63.5%) males. Men suffered more from apathy, speech, handwriting, and salivation, while women experienced more anxiety, depression, pain, and psychosis, after multivariable regression. Early-onset Parkinson’s disease (EOPD) and late-onset Parkinson’s disease (LOPD) were divided based on the 50-year-old cut-off age. They were represented by 989 (24.6%) and 2834 (70%) of the total, respectively, and EOPD patients had a higher duration of the disease and a higher positive family history.
期刊介绍：
npj Parkinson's Disease is a comprehensive open access journal that covers a wide range of research areas related to Parkinson's disease. It publishes original studies in basic science, translational research, and clinical investigations. The journal is dedicated to advancing our understanding of Parkinson's disease by exploring various aspects such as anatomy, etiology, genetics, cellular and molecular physiology, neurophysiology, epidemiology, and therapeutic development. By providing free and immediate access to the scientific and Parkinson's disease community, npj Parkinson's Disease promotes collaboration and knowledge sharing among researchers and healthcare professionals.
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