Bowel Preparation Quality in Patients Using Glucagon-Like Peptide-1 Agonists: A Systematic Review and Meta-Analysis

IF 7.5 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Gastrointestinal endoscopy Pub Date : 2025-08-20 DOI:10.1016/j.gie.2025.08.027

Zohaib Ahmed MD, Amna Iqbal MD, Syeda Faiza Arif, Connor Campbell MS4, Jared Fehlman MD, David James Allen, Wade Lee Smith MSc, Basmah Khalil MD, Faisal Kamal MD, Umair Iqbal, Ali Nawras MD, Yaseen Alastal MD, Douglas G. Adler MD

引用次数: 0

Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now the mainstay treatment for many chronic conditions including diabetes mellitus, obesity, heart failure and chronic kidney disease. GLP-1 RAs may affect bowel preparation for a colonoscopy by modifying intestinal motility and gastric emptying. We conducted a systematic review and meta-analysis to investigate the impact of GLP-1 RA use on bowel preparation quality, measured by the Boston Bowel Preparation Scale (BBPS), and the frequency of inadequate preparation events.

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使用胰高血糖素样肽-1激动剂患者的肠道准备质量：系统回顾和荟萃分析

胰高血糖素样肽-1受体激动剂（GLP-1 RAs）目前是许多慢性疾病的主要治疗方法，包括糖尿病、肥胖、心力衰竭和慢性肾脏疾病。GLP-1 RAs可能通过改变肠道运动和胃排空来影响结肠镜检查的肠道准备。我们进行了一项系统回顾和荟萃分析，以调查GLP-1 RA使用对肠准备质量的影响，以波士顿肠准备量表（BBPS）衡量，以及准备不足事件的频率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gastrointestinal endoscopy 医学-胃肠肝病学

CiteScore

10.30

自引率

7.80%

发文量

1441

审稿时长

38 days

期刊介绍： Gastrointestinal Endoscopy is a journal publishing original, peer-reviewed articles on endoscopic procedures for studying, diagnosing, and treating digestive diseases. It covers outcomes research, prospective studies, and controlled trials of new endoscopic instruments and treatment methods. The online features include full-text articles, video and audio clips, and MEDLINE links. The journal serves as an international forum for the latest developments in the specialty, offering challenging reports from authorities worldwide. It also publishes abstracts of significant articles from other clinical publications, accompanied by expert commentaries.