{"title":"Molecular characterization of a novel narnavirus from the plant-pathogenic fungus Colletotrichum gloeosporioides","authors":"Peiping Luo, Xuetuan Lin, Siyu Zhou, Daipeng Chen, Yinhui Sun, Li Zheng","doi":"10.1007/s00705-025-06391-6","DOIUrl":null,"url":null,"abstract":"<div><p>Here, we characterized a novel mycovirus, Colletotrichum gloeosporioides narnavirus 1 (CgNV1), isolated from <i>Colletotrichum gloeosporioides</i> strain T-19, a fungal pathogen responsible for anthracnose in various crops. The CgNV1 genome consists of a 3,628-nucleotide-long positive-sense single-stranded RNA (+ ssRNA) with a GC content of 51.93% and has a single open reading frame (ORF) encoding an RNA-dependent RNA polymerase (RdRp) of 1,155 amino acids (132.2 kDa). BLASTp analysis indicated that the CgNV1 RdRp shares the highest sequence identity (56.77%) with that of Erysiphe necator narnavirus 15. Phylogenetic analysis confirmed that CgNV1 is a distinct member of the family <i>Narnaviridae</i>. To our knowledge, this is the first report of a narnavirus infecting <i>C. gloeosporioides</i>, expanding the known diversity of mycoviruses associated with this phytopathogenic fungus.</p></div>","PeriodicalId":8359,"journal":{"name":"Archives of Virology","volume":"170 9","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Virology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00705-025-06391-6","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
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Abstract
Here, we characterized a novel mycovirus, Colletotrichum gloeosporioides narnavirus 1 (CgNV1), isolated from Colletotrichum gloeosporioides strain T-19, a fungal pathogen responsible for anthracnose in various crops. The CgNV1 genome consists of a 3,628-nucleotide-long positive-sense single-stranded RNA (+ ssRNA) with a GC content of 51.93% and has a single open reading frame (ORF) encoding an RNA-dependent RNA polymerase (RdRp) of 1,155 amino acids (132.2 kDa). BLASTp analysis indicated that the CgNV1 RdRp shares the highest sequence identity (56.77%) with that of Erysiphe necator narnavirus 15. Phylogenetic analysis confirmed that CgNV1 is a distinct member of the family Narnaviridae. To our knowledge, this is the first report of a narnavirus infecting C. gloeosporioides, expanding the known diversity of mycoviruses associated with this phytopathogenic fungus.
期刊介绍：
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.
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