Chemical Profile and Quantitative Comparison of Compounds of Different Botanical Parts of Pogostemon cablin From Different Geographical Regions

IF 1.7 4区医学 Q4 BIOCHEMICAL RESEARCH METHODS

Biomedical Chromatography Pub Date : 2025-08-23 DOI:10.1002/bmc.70201

Yameng Zhu, Huizi Ouyang, Zhoujing Feng, Linchang Fan, Xiunan Cao, Yanxu Chang, Jun He

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引用次数: 0

Abstract

In the present study, a comprehensive study on the chemical constituents of Pogostemon cablin (PC) based on plant metabolomics was conducted. A total of 72 nonvolatile and 72 volatile chemical components of PC were characterized by ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS) and gas chromatography–mass spectrometry (GC–MS), respectively. Subsequently, 15 nonvolatile and 14 volatile chemical components were identified as potential markers for discriminating between different botanical parts of PC. Furthermore, 20 major compounds of PC were quantitatively determined by ultra-high-performance liquid chromatography–mass spectrometry (UPLC-MS/MS) and the GC–MS method. Notably, the content of pogostone in the aerial part was the highest. Conversely, the content of other components in the leaves was relatively high, with patchouli alcohol being the highest. This study elucidates in detail the metabolic analysis of different botanical parts of PC and provides a reliable reference for its development and rationalization.

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不同地域广藿香不同植物部位化合物的化学特征及定量比较

本研究基于植物代谢组学对广藿香（Pogostemon cablin， PC）的化学成分进行了全面研究。采用超高效液相色谱-四极杆飞行时间质谱联用（UPLC-Q-TOF-MS）和气相色谱-质谱联用（GC-MS）对PC中72种非挥发性和72种挥发性化学成分进行了表征。随后，鉴定出15种非挥发性化学成分和14种挥发性化学成分作为鉴别不同植物性部位的潜在标记物。采用超高效液相色谱-质谱联用（UPLC-MS/MS）和气相色谱-质谱联用（GC-MS）法对20种主要化合物进行了定量分析。值得注意的是，地上部分的枸杞石含量最高。相反，其他成分的含量相对较高，以广藿香醇含量最高。本研究较详细地阐述了白藜芦醇不同植物部位的代谢分析，为其开发和合理化提供了可靠的参考。

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来源期刊

Biomedical Chromatography 生物-分析化学

CiteScore

3.60

自引率

5.60%

发文量

268

审稿时长

2.3 months

期刊介绍： Biomedical Chromatography is devoted to the publication of original papers on the applications of chromatography and allied techniques in the biological and medical sciences. Research papers and review articles cover the methods and techniques relevant to the separation, identification and determination of substances in biochemistry, biotechnology, molecular biology, cell biology, clinical chemistry, pharmacology and related disciplines. These include the analysis of body fluids, cells and tissues, purification of biologically important compounds, pharmaco-kinetics and sequencing methods using HPLC, GC, HPLC-MS, TLC, paper chromatography, affinity chromatography, gel filtration, electrophoresis and related techniques.