Community prevalence of at-risk state for bipolar disorder: Validation of the Korean version of Bipolar Prodrome Symptom Interview and Scale-Abbreviated Screen for Patients (BPSS-AS-P)

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry Pub Date : 2025-08-19 DOI:10.1016/j.ajp.2025.104669

Junhee Lee , Taeyoung Lee , Christoph U. Correll

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引用次数: 0

Abstract

Introduction

The progression towards early identification and intervention of bipolar disorder (BD) has been dampened by a scarcity of reliable early screening instruments for BD risk. The Bipolar Prodrome Symptom Interview and Scale–Abbreviated Screen for Patients (BPSS-AS-P) is a self-rated questionnaire devised to screen individuals at risk of developing BD but has not been validated in a community-dwelling individuals. The current study aimed to validate its psychometric properties and determine the optimal cut-off in a community sample.

Methods

The study included community-dwelling residents, aged 14–34, who underwent two-phased, semi-structured interviews. Among those, 138 individuals who screened positive on the Mood Disorder Questionnaire (MDQ) participated in the second stage interview by a psychiatrist and completed the BPSS-AS-P. The psychometric properties of the BPSS-AS-P were evaluated, including internal consistency, convergent validity, and optimal cut-offs.

Results

Fifty-eight individuals (42.0 % of the second stage interviewees or 4.2 % of the total participants) were identified as being at risk of developing BD (BDRisk+). The median (IQR) age was 25 (20–30) and 24 (18–29) years, for the BDRisk+ and BDRisk– individuals. The BPSS-AS-P showed very good internal consistency (Cronbach’s α=.89). The BPSS-AS-P raw summed total score was significantly positively correlated with BDRisk+ (P = .044), discriminating BDRisk+ from BDRisk– individuals (AUC=.800, P < .001) at a cut-off score= 25.

Conclusions

Among community-dwelling participants, prevalence of BDRisk+ individuals was 4.2 %. The BPSS-AS-P, a self-report questionnaire version of the semi-structured interview for identifying BDRisk+ individuals had satisfactory psychometric properties in a community sample. Future studies on the predictive validity of the BPSS-AS-P to predict full-blown BD are needed.

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双相情感障碍高危状态的社区患病率：韩国版双相前驱症状访谈和患者量表简化筛查（BPSS-AS-P）的验证

由于缺乏可靠的双相情感障碍风险早期筛查工具，双相情感障碍（BD）早期识别和干预的进展受到了阻碍。双相前驱症状访谈和患者量表简化筛查（BPSS-AS-P）是一份自评问卷，用于筛查有患双相障碍风险的个体，但尚未在社区居民中得到验证。目前的研究旨在验证其心理测量特性，并确定社区样本的最佳截止值。方法研究对象为14-34岁的社区居民，采用两阶段半结构化访谈。其中心境障碍问卷（MDQ）筛查阳性的138人参加了精神科医生的第二阶段访谈，并完成了BPSS-AS-P。评估了BPSS-AS-P的心理测量特性，包括内部一致性、收敛效度和最佳截止值。结果58人（占第二阶段受访者的42.0% %或总参与者的4.2% %）被确定为有发展为BD的风险（BDRisk+）。BDRisk+ 和BDRisk -个体的中位（IQR）年龄分别为25（20-30）岁和24（18-29）岁。BPSS-AS-P具有很好的内部一致性（Cronbach’s α= 0.89）。BPSS-AS-P原始总得分与BDRisk+ 呈显著正相关（P = ）。044)，区分brisk + 和brisk -个体（AUC= 0.800, P <； ）。001)，截止分数= 25。结论在社区居住的参与者中，brisk + 个体的患病率为4.2 %。BPSS-AS-P是半结构化访谈的自我报告问卷版本，用于识别BDRisk+ 个体在社区样本中具有令人满意的心理测量特性。需要进一步研究BPSS-AS-P对全面双相障碍的预测有效性。

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来源期刊

Asian journal of psychiatry Medicine-Psychiatry and Mental Health

CiteScore

12.70

自引率

5.30%

发文量

297

审稿时长

35 days

期刊介绍： The Asian Journal of Psychiatry serves as a comprehensive resource for psychiatrists, mental health clinicians, neurologists, physicians, mental health students, and policymakers. Its goal is to facilitate the exchange of research findings and clinical practices between Asia and the global community. The journal focuses on psychiatric research relevant to Asia, covering preclinical, clinical, service system, and policy development topics. It also highlights the socio-cultural diversity of the region in relation to mental health.