Biocompatible CMC-based hydrogel fiber systems: swelling control via trivalent ionic crosslinking

IF 2.8 4区 化学 Q3 POLYMER SCIENCE
Nilay Kahya
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Abstract

Carboxymethyl cellulose (CMC) is a hydrophilic and biocompatible polysaccharide widely employed in hydrogel systems. Herein, CMC-based fibers were ionically crosslinked using different trivalent cations, Al³⁺, Ce³⁺, and Fe³⁺, to investigate the effects of crosslinking type on water swelling behavior and surface morphology. Swelling studies were conducted in distilled water at room temperature, and the water uptake of each crosslinked sample was evaluated over time. The results showed that Al³⁺-CMC fibers had the highest swelling ratio, whereas Fe³⁺-treated fibers demonstrated more limited swelling due to their denser network structure. Ce³⁺-CMC fibers displayed intermediate behavior. Linear density analysis showed an increasing Tex trend from Al³⁺- to Ce³⁺- and Fe³⁺-crosslinked fibers, consistent with their respective swelling behaviors and morphological characteristics. To further understand the influence of crosslinking, fiber morphology was analyzed using scanning electron microscopy. The images revealed distinct differences in surface features, with Al³⁺-treated samples showing more pronounced surface roughness, while Fe³⁺-CMC fibers were smoother and more compact. These findings suggest that the choice of trivalent crosslinker significantly influences both the swelling characteristics and morphology of CMC fibers. The tunable properties of these ionically crosslinked fibers indicate their potential suitability for various applications such as controlled release systems, wound dressings, and biodegradable packaging materials.

Abstract Image

Abstract Image

生物相容性cmc基水凝胶纤维系统:通过三价离子交联控制膨胀
羧甲基纤维素(CMC)是一种广泛应用于水凝胶体系的亲水性和生物相容性多糖。本文采用不同的三价阳离子(Al³+、Ce³+和Fe³+)对cmc基纤维进行离子交联,研究交联类型对水膨胀行为和表面形貌的影响。在室温蒸馏水中进行溶胀研究,并随时间评估每个交联样品的吸水率。结果表明,Al³+ -CMC纤维的膨胀率最高,而Fe³+处理的纤维由于其更致密的网络结构,膨胀率更有限。Ce³+ -CMC纤维表现出中间行为。线密度分析显示,从Al + -到Ce + -和Fe + -交联纤维,Tex呈增加趋势,与它们各自的膨胀行为和形态特征一致。为了进一步了解交联的影响,用扫描电镜分析了纤维的形态。图像显示了表面特征的明显差异,Al³⁺处理过的样品表面粗糙度更明显,而Fe³⁺-CMC纤维更光滑、更致密。这些结果表明,三价交联剂的选择对CMC纤维的膨胀特性和形态都有显著影响。这些离子交联纤维的可调特性表明它们在控制释放系统、伤口敷料和可生物降解包装材料等各种应用中的潜在适用性。
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来源期刊
Journal of Polymer Research
Journal of Polymer Research 化学-高分子科学
CiteScore
4.70
自引率
7.10%
发文量
472
审稿时长
3.6 months
期刊介绍: Journal of Polymer Research provides a forum for the prompt publication of articles concerning the fundamental and applied research of polymers. Its great feature lies in the diversity of content which it encompasses, drawing together results from all aspects of polymer science and technology. As polymer research is rapidly growing around the globe, the aim of this journal is to establish itself as a significant information tool not only for the international polymer researchers in academia but also for those working in industry. The scope of the journal covers a wide range of the highly interdisciplinary field of polymer science and technology, including: polymer synthesis; polymer reactions; polymerization kinetics; polymer physics; morphology; structure-property relationships; polymer analysis and characterization; physical and mechanical properties; electrical and optical properties; polymer processing and rheology; application of polymers; supramolecular science of polymers; polymer composites.
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