[Development of a quality control indicator system for neonatal screening of inherited metabolic diseases in obstetric settings].

Q3 Medicine

中国当代儿科杂志 Pub Date : 2025-08-15 DOI:10.7499/j.issn.1008-8830.2412118

Hui Li, Jin Zhang, Dan-Feng Cao

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引用次数: 0

Abstract

Objectives: To develop a quality control indicator system for neonatal screening of inherited metabolic diseases in obstetric settings, so as to provide a standardized tool for quality control in clinical neonatal screening of inherited metabolic diseases.

Methods: From March to May 2024, a literature review combined with expert clinical experience was conducted to develop a preliminary questionnaire on quality control indicators for neonatal screening of inherited metabolic diseases. The final indicator system was established after two rounds of the Delphi method, and the Analytic Hierarchy Process was used to determine indicator weights.

Results: Sixteen questionnaires were distributed in each of the two consultation rounds, with a valid response rate of 100% for both. The expert authority coefficients were 0.863 and 0.876, respectively. Kendall's coefficient of concordance for the importance and feasibility of the indicators ranged from 0.091 to 0.125. The final indicator system comprised 3 primary indicators, 8 secondary indicators, and 28 tertiary indicators for neonatal screening of inherited metabolic diseases in obstetric settings.

Conclusions: The quality control indicator system developed using the Delphi method demonstrates a strong systematic structure, high clinical adaptability, and strong operability, and can be effectively applied to quality control in neonatal screening of inherited metabolic diseases in obstetric settings.

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[建立产科新生儿遗传代谢疾病筛查质量控制指标体系]。

目的：建立产科新生儿遗传代谢性疾病筛查质量控制指标体系，为新生儿遗传代谢性疾病临床筛查质量控制提供标准化工具。方法：于2024年3月至5月，通过文献查阅，结合专家临床经验，编制新生儿遗传代谢性疾病筛查质量控制指标初步问卷。通过两轮德尔菲法建立最终的指标体系，并采用层次分析法确定指标权重。结果：两轮会诊各发放问卷16份，有效回复率均为100%。专家权威系数分别为0.863和0.876。各指标重要性和可行性的肯德尔一致性系数为0.091 ~ 0.125。最终的指标体系包括3个一级指标、8个二级指标和28个三级指标，用于产科环境中新生儿遗传代谢疾病的筛查。结论：采用德尔菲法建立的质量控制指标体系系统性强、临床适应性强、可操作性强，可有效应用于产科新生儿遗传代谢性疾病筛查的质量控制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国当代儿科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.50

自引率

0.00%

发文量

5006

期刊介绍： The Chinese Journal of Contemporary Pediatrics (CJCP) is a peer-reviewed open access periodical in the field of pediatrics that is sponsored by the Central South University/Xiangya Hospital of Central South University and under the auspices of the Ministry of Education of China. It is cited as a source in the scientific and technological papers of Chinese journals, the Chinese Science Citation Database (CSCD), and is one of the core Chinese periodicals in the Peking University Library. CJCP has been indexed by MEDLINE/PubMed/PMC of the American National Library, American Chemical Abstracts (CA), Holland Medical Abstracts (EM), Western Pacific Region Index Medicus (WPRIM), Scopus and EBSCO. It is a monthly periodical published on the 15th of every month, and is distributed both at home and overseas. The Chinese series publication number is CN 43-1301/R；ISSN 1008-8830. The tenet of CJCP is to “reflect the latest advances and be open to the world”. The periodical reports the most recent advances in the contemporary pediatric field. The majority of the readership is pediatric doctors and researchers.