Shreyas B Jayade, Mariam Alavidze, Shweta K Tonny, Raghuveer K Halkar
{"title":"Drug-induced Sarcoid-like Reaction Presenting as Fascitis.","authors":"Shreyas B Jayade, Mariam Alavidze, Shweta K Tonny, Raghuveer K Halkar","doi":"10.1097/RLU.0000000000006058","DOIUrl":null,"url":null,"abstract":"<p><p>Drug-induced sarcoid-like reactions (DISRs) present complex challenges in clinical management. The most common presentation in FDG-PET/CT scan is bilateral symmetrical lymphadenopathy, and occasionally spleen and bone involvement. DISR presenting as fasciitis/ myofasciitis is extremely rare. We will discuss pre-chemo, post-chemo, and follow-up FDG-PET/ CT scans, exhibiting DISR-induced fasciitis and resolution of findings after cessation of immunotherapy. How to diagnose and manage DISR is still debatable. Histologic confirmation or short interval follow-up scans with resolution findings can lead to the diagnosis, depending on the severity of symptoms, cessation of therapy or continuation of therapy is instituted.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e589-e590"},"PeriodicalIF":9.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000006058","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/18 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Drug-induced sarcoid-like reactions (DISRs) present complex challenges in clinical management. The most common presentation in FDG-PET/CT scan is bilateral symmetrical lymphadenopathy, and occasionally spleen and bone involvement. DISR presenting as fasciitis/ myofasciitis is extremely rare. We will discuss pre-chemo, post-chemo, and follow-up FDG-PET/ CT scans, exhibiting DISR-induced fasciitis and resolution of findings after cessation of immunotherapy. How to diagnose and manage DISR is still debatable. Histologic confirmation or short interval follow-up scans with resolution findings can lead to the diagnosis, depending on the severity of symptoms, cessation of therapy or continuation of therapy is instituted.
期刊介绍:
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.