Stefania Iametti, Alessandra Bordoni, Mattia Di Nunzio
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引用次数: 0
Abstract
A plant-based diet is known to be nutrient-dense and rich in fibers, healthy fats, proteins, vitamins, and minerals. A diet rich in plant-based foods may help reduce the risk of chronic diseases such as cardiovascular disease and diabetes. As consumers become more health conscious, there is a growing interest in plant-based diets. In addition to providing essential nutrients, some food proteins may provide additional health benefits, as plant proteins are broken down into bioactive peptides during gastrointestinal digestion, often in dependence on previous processing. Bioactive peptides have several important functions in the body, including antioxidant, antimicrobial, immunomodulatory, and anti-hypertensive effects. To date, several reviews have provided an overview of the generation of bioactive peptides and their associated biological activities and putative health benefits in a range of animal-based foods, but information on plant-based foods is fragmented. We then systematically reviewed the existing literature reporting the release of bioactive peptides from plant-based food products and ingredients after in vitro digestion according to the INFOGEST protocol. The results reported in this review highlight that most of the bioactive peptides of plant origin exhibited antioxidant, anti-hypertensive, and anti-diabetic activity. The relationship between the structure and functionality of peptides and the major gaps in bioactive peptide research were also discussed, to focus on these aspects in future research. This may lead to a better understanding of the behavior of plant proteins in the human gastrointestinal tract, enhancing their contribution as sources of bioactive peptides.
期刊介绍:
BioFactors, a journal of the International Union of Biochemistry and Molecular Biology, is devoted to the rapid publication of highly significant original research articles and reviews in experimental biology in health and disease.
The word “biofactors” refers to the many compounds that regulate biological functions. Biological factors comprise many molecules produced or modified by living organisms, and present in many essential systems like the blood, the nervous or immunological systems. A non-exhaustive list of biological factors includes neurotransmitters, cytokines, chemokines, hormones, coagulation factors, transcription factors, signaling molecules, receptor ligands and many more. In the group of biofactors we can accommodate several classical molecules not synthetized in the body such as vitamins, micronutrients or essential trace elements.
In keeping with this unified view of biochemistry, BioFactors publishes research dealing with the identification of new substances and the elucidation of their functions at the biophysical, biochemical, cellular and human level as well as studies revealing novel functions of already known biofactors. The journal encourages the submission of studies that use biochemistry, biophysics, cell and molecular biology and/or cell signaling approaches.