Metal additive manufacturing of lattice-based orthopedic implants: A comprehensive review of requirements and design strategies

IF 31.6 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Science and Engineering: R: Reports Pub Date : 2025-08-20 DOI:10.1016/j.mser.2025.101075

Melika Babaei , Simone Murchio , Lorena Emanuelli , Raffaele De Biasi , Luigi Branca Vergano , Roberto Giuliani , Shuya Tian , Marie-Luise Wille , Filippo Berto , Massimo Pellizzari , Matteo Benedetti

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引用次数: 0

Abstract

This scoping review synthesizes recent advancements in the design and manufacturing of metallic additively manufactured lattice-based orthopedic implants. The review begins with an in-depth discussion on material selection, exploring the range of metals suitable for orthopedic applications, and progresses to detail the evolution of design methodologies, which now incorporate bio-inspired concepts and data-driven models such as inverse design. These innovative approaches significantly enhance the customization and functionality of bone implants, offering unprecedented opportunities for tailored patient care.

Additionally, the review analyzes the current standards and regulations that govern the development and implementation of these implants in clinical settings. It outlines the necessary steps and considerations for compliance, emphasizing the importance of these frameworks in ensuring the safe and effective transition of lattice-based orthopedic implants from theoretical models to practical solutions in healthcare.

By bridging the gap between cutting-edge research and clinical application, this review aims to serve as a crucial resource for researchers, engineers, and medical professionals. It not only encapsulates the state-of-the-art in implant technology but also highlights the collaborative efforts required to advance the field and overcome existing challenges. The ultimate goal is to pave the way for next-generation bone implants that are highly effective, safe, and optimized for individual patient needs.

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基于晶格的骨科植入物的金属增材制造：需求和设计策略的全面审查

本文综述了金属增材制造的基于晶格的骨科植入物的设计和制造方面的最新进展。回顾开始于对材料选择的深入讨论，探索适合骨科应用的金属范围，并进一步详细介绍设计方法的演变，现在包括生物启发概念和数据驱动模型，如逆向设计。这些创新的方法显著增强了骨植入物的定制和功能，为量身定制的患者护理提供了前所未有的机会。此外，本文还分析了在临床环境中管理这些植入物的开发和实施的现行标准和法规。它概述了必要的步骤和合规性的考虑，强调了这些框架的重要性，以确保安全有效地过渡到基于格的骨科植入物从理论模型到医疗保健的实际解决方案。通过弥合前沿研究和临床应用之间的差距，本综述旨在为研究人员、工程师和医学专业人员提供重要的资源。它不仅包含了最先进的植入技术，而且还强调了推进该领域和克服现有挑战所需的合作努力。最终目标是为下一代骨植入物铺平道路，这些骨植入物是高效、安全的，并且针对个体患者的需求进行了优化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Materials Science and Engineering: R: Reports 工程技术-材料科学：综合

CiteScore

60.50

自引率

0.30%

发文量

审稿时长

34 days

期刊介绍： Materials Science & Engineering R: Reports is a journal that covers a wide range of topics in the field of materials science and engineering. It publishes both experimental and theoretical research papers, providing background information and critical assessments on various topics. The journal aims to publish high-quality and novel research papers and reviews. The subject areas covered by the journal include Materials Science (General), Electronic Materials, Optical Materials, and Magnetic Materials. In addition to regular issues, the journal also publishes special issues on key themes in the field of materials science, including Energy Materials, Materials for Health, Materials Discovery, Innovation for High Value Manufacturing, and Sustainable Materials development.