Trends in the dispensing of opioids for pain and concurrent benzodiazepine use among First Nations People in Ontario, Canada, from 2013 to 2021.

IF 2.6 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Canadian Journal of Public Health-Revue Canadienne De Sante Publique Pub Date : 2025-08-18 DOI:10.17269/s41997-025-01097-3

Alice Holton, Tianru Wang, Bisola Hamzat, Sacha Bragg, Bernadette deGonzague, Graham Mecredy, Tonya Campbell, Tony Antoniou, Lorrilee McGregor, Jonathan Bertram, Tara Gomes

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引用次数: 0

Abstract

Objectives: To investigate dispensing trends and the characteristics of First Nations People in Ontario dispensed an opioid for pain and concurrent benzodiazepine treatment.

Methods: We conducted a population-based serial cross-sectional study by quarter of registered (Status) First Nations People in Ontario who were dispensed an opioid for pain between April 1, 2013, and December 31, 2021. We reported quarterly trends in prevalent and incident opioid dispensing (rates per 1000 people), and the prevalence of concurrent benzodiazepine use among individuals receiving opioids for pain. For the final year (2021), we stratified rates by age, place of residence (within or outside First Nations communities), and sex.

Results: Between 2013 and 2021, the quarterly rate of opioid dispensing for pain decreased by 25.0% among First Nations People in Ontario, from 74.7 to 56.0 per 1000 people. In stratified analyses for the year 2021, opioid use for pain was more frequent among First Nations People living outside versus within First Nations communities (118.2 vs. 91.2 per 1000, respectively) and among females relative to males (124.6 and 93.9 per 1000, respectively). Concurrent prescription benzodiazepine use among First Nations People receiving a prescription opioid for pain decreased from 20.9% in Q2 2013 to 16.7% in Q4 2021. In stratified analyses, concurrent use was more prevalent among females, adults aged ≥ 65 years, and First Nations People living outside First Nations communities.

Conclusion: Opioid analgesic prescribing patterns for First Nations People living in Ontario indicate a decrease in both overall prescribing rates and concurrent benzodiazepine use.

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2013年至2021年加拿大安大略省第一民族使用阿片类药物治疗疼痛和同时使用苯二氮卓类药物的趋势

目的：调查安大略省第一民族使用阿片类药物治疗疼痛和同时使用苯二氮卓类药物治疗的趋势和特点。方法：在2013年4月1日至2021年12月31日期间，我们对安大略省四分之一的注册（状态）第一民族进行了一项基于人群的系列横断面研究。我们报告了流行和事件阿片类药物分配的季度趋势（每1000人的比率），以及在接受阿片类药物治疗疼痛的个体中同时使用苯二氮卓类药物的流行情况。在最后一年（2021年），我们按年龄、居住地（在原住民社区内或外）和性别对比率进行了分层。结果：2013年至2021年期间，安大略省第一民族的阿片类药物分配率下降了25.0%，从每千人74.7人降至56.0人。在2021年的分层分析中，居住在外面的第一民族比居住在第一民族社区内的第一民族更频繁地使用阿片类药物治疗疼痛（分别为118.2比91.2 / 1000），女性相对于男性（分别为124.6和93.9 / 1000）。在接受处方阿片类药物治疗疼痛的原住民中，苯二氮卓类药物的同时使用从2013年第二季度的20.9%下降到2021年第四季度的16.7%。在分层分析中，同时用药在女性、年龄≥65岁的成年人和居住在第一民族社区以外的第一民族人群中更为普遍。结论：居住在安大略省的原住民的阿片类镇痛药处方模式表明，总体处方率和苯二氮卓类药物的同时使用都有所下降。

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来源期刊

Canadian Journal of Public Health-Revue Canadienne De Sante Publique PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

6.10

自引率

4.70%

发文量

128

期刊介绍： The Canadian Journal of Public Health is dedicated to fostering excellence in public health research, scholarship, policy and practice. The aim of the Journal is to advance public health research and practice in Canada and around the world, thus contributing to the improvement of the health of populations and the reduction of health inequalities. CJPH publishes original research and scholarly articles submitted in either English or French that are relevant to population and public health. CJPH is an independent, peer-reviewed journal owned by the Canadian Public Health Association and published by Springer. Énoncé de mission La Revue canadienne de santé publique se consacre à promouvoir l’excellence dans la recherche, les travaux d’érudition, les politiques et les pratiques de santé publique. Son but est de faire progresser la recherche et les pratiques de santé publique au Canada et dans le monde, contribuant ainsi à l’amélioration de la santé des populations et à la réduction des inégalités de santé. La RCSP publie des articles savants et des travaux inédits, soumis en anglais ou en français, qui sont d’intérêt pour la santé publique et des populations. La RCSP est une revue indépendante avec comité de lecture, propriété de l’Association canadienne de santé publique et publiée par Springer.