Evaluation of the risk-benefit of thoracic paravertebral nerve block combined with propofol anesthesia and inhalation combined anesthesia for radical treatment in elderly lung cancer based on diaphragm functional parameters.

Abstract

To evaluate the benefit-risk of thoracic complex propofol anesthesia for elderly lung cancer based on diaphragm function parameters. 137 elderly patients with lung cancer undergoing radical resection of thoracic surgery at Hangzhou First People's Hospital were selected. The patients were divided into: paravertebral complex propofol anesthesia (PPA, N = 68) group and static aspiration compound anesthesia (SGA, N. = 69) group. In the PPA group, the amount of remifentanil, postoperative sufentanl, 24h, anesthesia onset time, eye opening time, directional force recovery time, instruction time, IL-10, 6h, 12h, 48 h VAS score, active cough at 6h, 12h, 24 h, postoperative respiratory depression, upper airway obstruction, pulmonary complications were significantly lower than the SGA group (P <0.05), The diaphragm function parameters DTF, DD and diaphragm contraction velocity were significantly higher than those in the SGA group (P> 0.05); The benefit values of the PPA and SGA groups were 83, 47, Risk values were 17, respectively, 39, Benefit-total risk of 55, 36. The benefit-risk value was highest in PPA group. PPA anesthesia can not only effectively improve the effect of radical resection of elderly lung cancer on diaphragm function, but also has the characteristics of high anesthesia quality and few adverse reactions.