Prenatal diagnosis conventional/four-dimensional direct volume rendering fetal echocardiography pregnancy and postnatal outcomes of isolated anomalous course of left brachiocephalic vein.

IF 2.3 3区 医学 Q2 PEDIATRICS
Balaganesh Karmegaraj, Sowmya Vijayakumar
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引用次数: 0

Abstract

Background: Advances in fetal echocardiography, including conventional 2-dimensional (D) and 3-D/4-D imaging techniques, have improved our understanding of upper mediastinal vessels.

Objective: To study the prenatal imaging characteristics, pregnancy, and postnatal outcomes in fetuses with an isolated anomalous course of the left brachiocephalic vein.

Materials and methods: This retrospective study, conducted between October 2019 and July 2024, examined fetuses with an isolated anomalous course of the left brachiocephalic vein. These cases underwent conventional 2-D and 3-D/4-D spatiotemporal image correlation echocardiography at Sowmi Pediatric Heart Centre, Tirunelveli, India. The inclusion criteria encompassed all fetuses with an isolated anomalous course of the left brachiocephalic vein, whereas those with associated congenital heart defects or missing postnatal follow-up were excluded from the analysis.

Results: A total of 2,083 fetal echocardiograms were performed during the study period. In total, 331 fetal cardiac abnormalities were detected. Twelve fetuses with isolated anomalous course of left brachiocephalic vein were included in the study. Intrathymic left brachiocephalic vein was observed in nine fetuses, extrathymic left brachiocephalic vein in two fetuses, and retroaortic left brachiocephalic vein in one fetus. Quadruple marker screening in five cases yielded normal results. Invasive genetic testing performed in the case with retroaortic left brachiocephalic vein showed normal findings. Postnatally, no dysmorphism was observed in any fetus. All fetuses were delivered at term, had an uneventful postnatal period, underwent at least 3 months of follow-up, and were reassured.

Conclusion: Though the indication for referral for this fetal extracardiac anomaly was to rule out critical congenital heart disease, proper prenatal imaging of this benign finding will avoid unnecessary confusion, in utero referral to tertiary pediatric heart center for delivery and invasive genetic tests.

孤立性左头臂静脉异常走行的产前诊断常规/四维直接容积描画胎儿超声心动图妊娠及产后结局。
背景:胎儿超声心动图的进步,包括传统的二维(D)和三维/四维成像技术,提高了我们对上纵隔血管的认识。目的:探讨孤立性左头臂静脉异常胎儿的产前影像学特征、妊娠及产后预后。材料和方法:本回顾性研究于2019年10月至2024年7月期间进行,检查了左侧头臂静脉孤立异常的胎儿。这些病例在印度Tirunelveli的Sowmi儿科心脏中心接受了常规的二维和三维/ 4d时空图像相关超声心动图检查。纳入标准包括所有伴有孤立的左头臂静脉异常的胎儿,而伴有先天性心脏缺陷或缺少产后随访的胎儿则被排除在分析之外。结果:研究期间共进行了2083例胎儿超声心动图检查。总共检测到331例胎儿心脏异常。本研究纳入了12例孤立性左头臂静脉异常的胎儿。9例胎儿胸腺内可见左头臂静脉,2例胎儿胸腺外可见左头臂静脉,1例胎儿主动脉后可见左头臂静脉。五例四联标记物筛查结果正常。在主动脉后左头臂静脉的病例中进行了侵入性基因检测,结果正常。出生后,未观察到任何胎儿畸形。所有的胎儿都在足月分娩,有一个平静的产后时期,接受了至少3个月的随访,并得到了保证。结论:虽然这种胎儿心外异常的转诊指征是为了排除严重的先天性心脏病,但对这种良性发现进行适当的产前成像将避免不必要的混淆,在子宫内转诊到第三儿科心脏中心进行分娩和侵入性基因检测。
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来源期刊
Pediatric Radiology
Pediatric Radiology 医学-核医学
CiteScore
4.40
自引率
17.40%
发文量
300
审稿时长
3-6 weeks
期刊介绍: Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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