Prevalence of Burning Mouth Syndrome in Parkinson's Disease: A Prospective Case-Control Study.

IF 2.9 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Oral diseases Pub Date : 2025-08-18 DOI:10.1111/odi.70069

Anne Mishellany-Dutour, Céline Melin, Ingrid De Chazeron, Frank Durif, Radhouane Dallel, Christelle Gremeau-Richard

{"title":"Prevalence of Burning Mouth Syndrome in Parkinson's Disease: A Prospective Case-Control Study.","authors":"Anne Mishellany-Dutour, Céline Melin, Ingrid De Chazeron, Frank Durif, Radhouane Dallel, Christelle Gremeau-Richard","doi":"10.1111/odi.70069","DOIUrl":null,"url":null,"abstract":"Objective: To determine the prevalence of Burning mouth syndrome (BMS) in patients with Parkinson's disease (PD) and compare it with an age- and sex-matched control group.Methods: The study included 150 PD patients and 150 age- and sex-matched control subjects. Participants were asked about any possible burning or tingling sensation in the oral mucosa. Those who responded positively underwent a clinical examination and blood analysis to help in diagnosing BMS.Results: Prior to clinical examination, the prevalence of probable BMS was 6.7% (10/150) in PD patients and 2% (3/150) in the control group. After the clinical examination, 6 participants were excluded (3 from each group), resulting in a BMS prevalence of 4.7% in the PD group (7/150) and 0% in the control group (0/150). The difference in prevalence between the two groups was statistically significant (p = 0.015). Patients reported that their BMS symptoms began either after or around the time of their PD diagnosis.Conclusions: BMS is more prevalent in PD patients than in the general population, indicating a potential role of dopaminergic system dysfunction in BMS pathophysiology. The onset of BMS symptoms after or around the time of PD diagnosis suggests that BMS may be a secondary condition.","PeriodicalId":19615,"journal":{"name":"Oral diseases","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oral diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/odi.70069","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To determine the prevalence of Burning mouth syndrome (BMS) in patients with Parkinson's disease (PD) and compare it with an age- and sex-matched control group.

Methods: The study included 150 PD patients and 150 age- and sex-matched control subjects. Participants were asked about any possible burning or tingling sensation in the oral mucosa. Those who responded positively underwent a clinical examination and blood analysis to help in diagnosing BMS.

Results: Prior to clinical examination, the prevalence of probable BMS was 6.7% (10/150) in PD patients and 2% (3/150) in the control group. After the clinical examination, 6 participants were excluded (3 from each group), resulting in a BMS prevalence of 4.7% in the PD group (7/150) and 0% in the control group (0/150). The difference in prevalence between the two groups was statistically significant (p = 0.015). Patients reported that their BMS symptoms began either after or around the time of their PD diagnosis.

Conclusions: BMS is more prevalent in PD patients than in the general population, indicating a potential role of dopaminergic system dysfunction in BMS pathophysiology. The onset of BMS symptoms after or around the time of PD diagnosis suggests that BMS may be a secondary condition.

查看原文本刊更多论文

帕金森病患者灼口综合征的患病率：一项前瞻性病例对照研究

目的：了解帕金森病（PD）患者灼口综合征（BMS）的患病率，并与年龄和性别匹配的对照组进行比较。方法：研究对象为150例PD患者和150例年龄、性别匹配的对照组。参与者被问及口腔粘膜是否有灼烧感或刺痛感。那些反应积极的人接受了临床检查和血液分析，以帮助诊断BMS。结果：临床检查前，PD患者疑似BMS患病率为6.7%(10/150)，对照组为2%（3/150）。临床检查后，6名参与者被排除（每组3名），结果PD组BMS患病率为4.7%(7/150)，对照组为0%（0/150）。两组患病率差异有统计学意义（p = 0.015）。患者报告称，他们的BMS症状是在PD诊断后或前后开始的。结论：BMS在PD患者中比在普通人群中更普遍，提示多巴胺能系统功能障碍在BMS病理生理中的潜在作用。在PD诊断后或前后出现BMS症状表明BMS可能是继发性疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Oral diseases 医学-牙科与口腔外科

CiteScore

7.60

自引率

5.30%

发文量

325

审稿时长

4-8 weeks

期刊介绍： Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.