Effect of progesterone sequential therapy on follicle stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) in perimenopausal dysfunctional uterine bleeding.

IF 1.5 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Medical Biochemistry Pub Date : 2025-06-13 DOI:10.5937/jomb0-53229

Song Wu, Huiru Wang, Yuwei Zhao, Bo Tang, Qi Zhang, Dapeng Li

引用次数: 0

Abstract

Background: Perimenopausal dysfunctional uterine bleeding (PDUB) is a common gynaecological disease with various clinical treatment options. The objective of this work was to investigate the clinical effect of female progesterone sequential therapy (FPST) on PDUB and follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2).

Methods: 140 cases of PDUB patients were enrolled and randomly rolled into an observation (Obs) group and a control (Ctrl) group, with 70 cases in each. The patients in the Ctrl group were given pure curettage treatment, and those in the Obs group were supplemented with FPST based on the intervention in the Ctrl group.

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黄体酮序贯治疗对围绝经期功能失调性子宫出血促卵泡激素（FSH）、黄体生成素（LH）和雌二醇（E2）的影响。

背景：围绝经期功能失调性子宫出血（PDUB）是一种常见的妇科疾病，临床治疗方法多种多样。本研究旨在探讨雌孕酮序贯治疗（FPST）对PDUB和促卵泡激素（FSH）、黄体生成素（LH）、雌二醇（E2）的临床影响。方法：选取140例PDUB患者，随机分为观察组（Obs）和对照组（Ctrl），每组70例。对照组给予单纯刮痧治疗，Obs组在对照组干预的基础上辅以FPST治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

3.00

自引率

12.00%

发文量

审稿时长

>12 weeks

期刊介绍： The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly. The Journal publishes original scientific and specialized articles on all aspects of clinical and medical biochemistry, molecular medicine, clinical hematology and coagulation, clinical immunology and autoimmunity, clinical microbiology, virology, clinical genomics and molecular biology, genetic epidemiology, drug measurement, evaluation of diagnostic markers, new reagents and laboratory equipment, reference materials and methods, reference values, laboratory organization, automation, quality control, clinical metrology, all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.