Evaluation of the sensitive skin syndrome and the effect of a dermo-cosmetic treatment in Thai and Polish subjects.

IF 2.5 4区 医学 Q2 DERMATOLOGY
Helena Polena, Sylwia Czaińska, Benoît Cadars, Ewa Chlebus, Monika Serafin, Waranya Boonchai, Pichanee Chaweekulrat, Silada Kanokrungsee, Marlène Chavagnac-Bonneville, Christelle Graizeau, Michèle Sayag, Elodie Prestat-Marquis
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引用次数: 0

Abstract

Objective: Sensitive skin syndrome (SSS) affects individuals from all ethnic groups. However, studies across different populations remain limited, despite recognised differences between populations. Thus, we examined SSS in Thai and Polish subjects, assessing the tolerance and efficacy of a dermo-cosmetic product in both populations.

Methods: Thai participants were involved in a 28-day open-label study, while Polish subjects took part in a 56-day double-blind, randomised study comparing the product with a control cream. Clinical and functional signs were evaluated, alongside quality of life (QoL) using the Burden of Sensitive Skin (BoSS) questionnaire.

Results: The product was well tolerated in both groups over time, leading to significant improvements in all clinical and functional signs (p < 0.05 to p < 0.001) and enhancing QoL (p < 0.005 in Thailand; p < 0.001 in Poland). At baseline, Polish subjects exhibited greater redness and higher BoSS scores to questions relating to visual signs (p < 0.001). Conversely, Thai participants reported more pronounced tingling, pain and itching, along with higher BoSS scores relating to sensory symptoms (p < 0.001).

Conclusions: The study highlights differences existing in the perception of SSS symptoms between a Thai and Polish population and demonstrates that the dermo-cosmetic cream effectively alleviates SSS symptoms and improves QoL in both ethnic groups.

评估泰国和波兰受试者的敏感皮肤综合征和皮肤美容治疗的效果。
目的:敏感性皮肤综合征(SSS)可影响各个民族的个体。然而,尽管人们认识到不同人群之间存在差异,但对不同人群的研究仍然有限。因此,我们研究了泰国和波兰受试者的SSS,评估了两种人群对皮肤化妆品的耐受性和疗效。方法:泰国参与者参与了一项为期28天的开放标签研究,而波兰受试者参加了一项为期56天的双盲随机研究,将该产品与对照霜进行比较。使用敏感皮肤负担(BoSS)问卷评估临床和功能体征以及生活质量(QoL)。结果:随着时间的推移,该产品在两组中耐受性良好,导致所有临床和功能体征显着改善(p)结论:该研究强调了泰国和波兰人群对SSS症状的感知存在差异,并证明真皮美容霜有效缓解了SSS症状并改善了两个民族的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.60
自引率
4.30%
发文量
73
期刊介绍: The Journal publishes original refereed papers, review papers and correspondence in the fields of cosmetic research. It is read by practising cosmetic scientists and dermatologists, as well as specialists in more diverse disciplines that are developing new products which contact the skin, hair, nails or mucous membranes. The aim of the Journal is to present current scientific research, both pure and applied, in: cosmetics, toiletries, perfumery and allied fields. Areas that are of particular interest include: studies in skin physiology and interactions with cosmetic ingredients, innovation in claim substantiation methods (in silico, in vitro, ex vivo, in vivo), human and in vitro safety testing of cosmetic ingredients and products, physical chemistry and technology of emulsion and dispersed systems, theory and application of surfactants, new developments in olfactive research, aerosol technology and selected aspects of analytical chemistry.
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