Preventing HIV with injectable lenacapavir: WHO recommendation

Abstract

The World Health Organization (WHO) released new guidelines in July recommending the use of injectable lenacapavir (LEN) twice a year as an additional pre-exposure prophylaxis (PrEP) option for HIV prevention. The landmark policy could help reshape the global HIV response, according to WHO. The guidelines were issued at the 13th International AIDS Society Conference (IAS 2025) on HIV Science, in Kigali, Rwanda.