Ya. A. Kulinich, I. D. Puryskin, V. V. Tolmacheva, A. O. Melekhin, V. V. Apyari, S. G. Dmitrienko
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引用次数: 0
Abstract
Magnetic hypercrosslinked polystyrene (MHCPS) is proposed for the group adsorption and preconcentration of quinolones. The conditions for magnetic solid-phase extraction are selected as follows: 25 mL of solution (pH 6), sorbent mass 20 mg, and sorption time 20 min. The analytes have been desorbed with 2 mL of methanol. It is shown that the sorbent provides the quantitative extraction of all 23 studied compounds not only from aqueous solutions, but also from milk, bypassing the deproteinization stage. The determination is carried out by HPLC-tandem mass spectrometry using matrix calibration. The limits of detection and determination for quinolones are 0.012–0.12 and 0.04–0.4 μg/L, respectively, which are below their maximum residue levels in milk.
期刊介绍：
The Journal of Analytical Chemistry is an international peer reviewed journal that covers theoretical and applied aspects of analytical chemistry; it informs the reader about new achievements in analytical methods, instruments and reagents. Ample space is devoted to problems arising in the analysis of vital media such as water and air. Consideration is given to the detection and determination of metal ions, anions, and various organic substances. The journal welcomes manuscripts from all countries in the English or Russian language.
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