{"title":"Transformed L1 Regularization for Sparse Photoacoustic Tomography","authors":"Xueyan Liu;Lu Wang;Xin Wang;Ziqi Hao;Xiaolong Hu","doi":"10.1109/JPHOT.2025.3596236","DOIUrl":null,"url":null,"abstract":"Photoacoustic Tomography (PAT) is an advanced imaging technology that combines optical and acoustic methods to visualize the distribution of light absorption within biological tissues with high spatial resolution. The reconstruction of PAT images from incomplete and noisy experimental data is an ill-posed problem that requires regularization techniques to ensure meaningful and stable solutions. In this study, a transform L1 (TL1) regularization model was proposed to improve the quality of PAT images, which was evaluated by numerical simulation and tissue phantom experiments. Based on various numerical and tissue phantom scenarios, Gaussian noise levels of 10 to 30 dB, and multiple parameter configurations, the TL1 method consistently demonstrates shows consistent advantages over the Lp-norm (<inline-formula><tex-math>$0 \\leq p \\leq 2$</tex-math></inline-formula>) regularization methods in terms of image quality, computational efficiency, and noise robustness. This finding has important implications for improving sparse sampling PAT algorithms, and also provides valuable insights for the development of biomedical applications in the future.","PeriodicalId":13204,"journal":{"name":"IEEE Photonics Journal","volume":"17 5","pages":"1-11"},"PeriodicalIF":2.4000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11119050","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Photonics Journal","FirstCategoryId":"5","ListUrlMain":"https://ieeexplore.ieee.org/document/11119050/","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
引用次数: 0
Abstract
Photoacoustic Tomography (PAT) is an advanced imaging technology that combines optical and acoustic methods to visualize the distribution of light absorption within biological tissues with high spatial resolution. The reconstruction of PAT images from incomplete and noisy experimental data is an ill-posed problem that requires regularization techniques to ensure meaningful and stable solutions. In this study, a transform L1 (TL1) regularization model was proposed to improve the quality of PAT images, which was evaluated by numerical simulation and tissue phantom experiments. Based on various numerical and tissue phantom scenarios, Gaussian noise levels of 10 to 30 dB, and multiple parameter configurations, the TL1 method consistently demonstrates shows consistent advantages over the Lp-norm ($0 \leq p \leq 2$) regularization methods in terms of image quality, computational efficiency, and noise robustness. This finding has important implications for improving sparse sampling PAT algorithms, and also provides valuable insights for the development of biomedical applications in the future.
期刊介绍:
Breakthroughs in the generation of light and in its control and utilization have given rise to the field of Photonics, a rapidly expanding area of science and technology with major technological and economic impact. Photonics integrates quantum electronics and optics to accelerate progress in the generation of novel photon sources and in their utilization in emerging applications at the micro and nano scales spanning from the far-infrared/THz to the x-ray region of the electromagnetic spectrum. IEEE Photonics Journal is an online-only journal dedicated to the rapid disclosure of top-quality peer-reviewed research at the forefront of all areas of photonics. Contributions addressing issues ranging from fundamental understanding to emerging technologies and applications are within the scope of the Journal. The Journal includes topics in: Photon sources from far infrared to X-rays, Photonics materials and engineered photonic structures, Integrated optics and optoelectronic, Ultrafast, attosecond, high field and short wavelength photonics, Biophotonics, including DNA photonics, Nanophotonics, Magnetophotonics, Fundamentals of light propagation and interaction; nonlinear effects, Optical data storage, Fiber optics and optical communications devices, systems, and technologies, Micro Opto Electro Mechanical Systems (MOEMS), Microwave photonics, Optical Sensors.