Angry without Borders: Global prevalence and factors of intermittent explosive disorder: A systematic review and meta-analysis

IF 12.2 1区心理学 Q1 PSYCHOLOGY, CLINICAL

Clinical Psychology Review Pub Date : 2025-08-15 DOI:10.1016/j.cpr.2025.102643

Fangqing Liu , Xiaoshan Yin

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Abstract

This systematic review and meta-analysis aimed to synthesise global data on the prevalence, determinants, and moderators of Intermittent Explosive Disorder (IED). Analysing 29 studies (N = 182,112 participants across 17 countries), pooled lifetime and 12-month prevalence estimates were 5.1 % (95 % CI: 3.4–7.5 %) and 4.4 % (95 % CI: 2.9–6.7 %), respectively. Prevalence varied significantly across subgroups, with higher rates in clinical (10.5 %), refugee (8.5 %), and adolescent populations. Male gender (OR = 3.39), younger age, trauma exposure, and psychiatric comorbidities (mood, anxiety, and substance use disorders) emerged as robust risk factors. Studies using DSM-5 criteria reported lower prevalence than DSM-IV. Regional disparities were notable, with elevated rates in conflict-affected and Global South regions. Heterogeneity was partially explained by population type, diagnostic criteria, and sociocultural context. Findings underscore the multifactorial etiology of IED, shaped by biological vulnerabilities, trauma, and structural adversities. A tiered intervention framework integrating universal prevention, targeted therapies, and policy advocacy is therefore proposed to address its global burden.

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愤怒无国界：间歇性爆发性精神障碍的全球患病率和影响因素：一项系统回顾和荟萃分析

本系统综述和荟萃分析旨在综合有关间歇性爆炸障碍（IED）患病率、决定因素和调节因素的全球数据。分析了29项研究（17个国家的182,112名参与者），汇总终生和12个月患病率估计值分别为5.1% （95% CI: 3.4 - 7.5%）和4.4% （95% CI: 2.9 - 6.7%）。不同亚组的患病率差异显著，临床人群（10.5%）、难民人群（8.5%）和青少年人群的患病率较高。男性性别（OR = 3.39）、年轻、创伤暴露和精神合并症（情绪、焦虑和物质使用障碍）成为强有力的危险因素。使用DSM-5标准的研究报告的患病率低于DSM-IV。地区差异显著，受冲突影响地区和全球南方地区的比率较高。异质性部分可以由人群类型、诊断标准和社会文化背景来解释。研究结果强调了IED的多因素病因，由生物脆弱性、创伤和结构性逆境形成。因此，提出了一个整合普遍预防、靶向治疗和政策宣传的分层干预框架，以解决其全球负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Psychology Review PSYCHOLOGY, CLINICAL-

CiteScore

23.10

自引率

1.60%

发文量

期刊介绍： Clinical Psychology Review serves as a platform for substantial reviews addressing pertinent topics in clinical psychology. Encompassing a spectrum of issues, from psychopathology to behavior therapy, cognition to cognitive therapies, behavioral medicine to community mental health, assessment, and child development, the journal seeks cutting-edge papers that significantly contribute to advancing the science and/or practice of clinical psychology. While maintaining a primary focus on topics directly related to clinical psychology, the journal occasionally features reviews on psychophysiology, learning therapy, experimental psychopathology, and social psychology, provided they demonstrate a clear connection to research or practice in clinical psychology. Integrative literature reviews and summaries of innovative ongoing clinical research programs find a place within its pages. However, reports on individual research studies and theoretical treatises or clinical guides lacking an empirical base are deemed inappropriate for publication.