Placental Growth Factor Diagnostic Testing: An Opportunity to Transform Pregnancy Care for Patients With Suspected Preeclampsia in Canada

IF 2.2 Q2 OBSTETRICS & GYNECOLOGY

Journal of obstetrics and gynaecology Canada Pub Date : 2025-08-14 DOI:10.1016/j.jogc.2025.103076

Kelsey McLaughlin PhD , Melanie C. Audette MD, PhD , Harrison Banner MD, MSc , Jon Barrett MB, MD , Emmanuel Bujold MD, MSc , Honzer Chen MD , Nicole Cohen MD , Tina Delaney MD , Ernesto A. Figueiro-Filho MD, PhD , Rachel A. Gladstone MD, MSc , Venu Jain MD, PhD , Jessica Liauw MD, MSc , Isabelle Malhamé MD, MSc , Elad Mei-Dan MD , Nir Melamed MD, MSc , Kellie E. Murphy MD, MSc , Christopher M. Nash MD , Christy Pylypjuk MD, MSc , Naila Ramji MD, MSc , Anjana Ravi Chandran MSc , John W. Snelgrove MD, MSc

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引用次数: 0

Abstract

Preeclampsia is a leading cause of maternal morbidity and adverse perinatal outcomes in Canada. Growing evidence supports the novel blood-based biomarker placental growth factor (PlGF) as a diagnostic test to accelerate the timely diagnosis of preeclampsia, enhancing care for hypertensive pregnant patients. Despite national endorsement, challenges like regional disparities and test standardization hinder PlGF implementation. The Canadian PlGF Strategy & Research Consortium convened with representation from clinicians, researchers, and patient partners to discuss the current state of PlGF testing. We universally agreed there is an urgent need to implement diagnostic PlGF testing to improve maternal and perinatal outcomes in Canada.

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胎盘生长因子（PlGF）诊断测试：一个机会，以改变妊娠护理患者的怀疑先兆子痫在加拿大。

在加拿大，先兆子痫是产妇发病和不良围产期结局的主要原因。越来越多的证据支持新的基于血液的生物标志物胎盘生长因子（PlGF）作为一种诊断试验，加速先兆子痫的及时诊断，加强对高血压妊娠患者的护理。尽管国家认可，但地区差异和测试标准化等挑战阻碍了PlGF的实施。加拿大PlGF战略与研究联盟召集了来自临床医生、研究人员和患者合作伙伴的代表，讨论了PlGF检测的现状。我们普遍认为，迫切需要实施诊断性PlGF测试，以改善加拿大的孕产妇和围产期结局。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of obstetrics and gynaecology Canada OBSTETRICS & GYNECOLOGY-

CiteScore

3.30

自引率

5.60%

发文量

302

审稿时长

32 days

期刊介绍： Journal of Obstetrics and Gynaecology Canada (JOGC) is Canada"s peer-reviewed journal of obstetrics, gynaecology, and women"s health. Each monthly issue contains original research articles, reviews, case reports, commentaries, and editorials on all aspects of reproductive health. JOGC is the original publication source of evidence-based clinical guidelines, committee opinions, and policy statements that derive from standing or ad hoc committees of the Society of Obstetricians and Gynaecologists of Canada. JOGC is included in the National Library of Medicine"s MEDLINE database, and abstracts from JOGC are accessible on PubMed.