Multicentric prospective study on computed tomography-guided periradicular infiltration and facet joint infiltration.

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Daniel Cantré, Lars Gerigk, Simon David Sprengel, Christian Plathow, Iris Burkholder, Marc-André Weber, Anna Schedler, Christoph Rehnitz
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引用次数: 0

Abstract

Purpose: Evaluation of the success of periradicular infiltration and facet joint infiltration in a multicenter and prospective approach.

Materials and methods: 114 patients undergoing therapeutic nerve root or facet joint infiltration for radicular and/or facet joint symptoms between the first lumbar and the first sacral segments were prospectively and consecutively enrolled across nine participating study centers in Germany. These centers provide CT-guided pain procedures continuously over a period of 96 months. Assessment was carried out by means of a systematic patient survey including pain questionnaires. The severity of the pain and the impairment caused by pain were assessed using 11-point Numerical Rating Scales.

Results: CT-guided periradicular infiltration and facet joint infiltration significantly reduced pain levels and substantially reduced pain frequency at all time points and up to three months after the last intervention. All pain related characteristics (i.e. actual pain, average pain level, maximum pain level) were significantly (95% confidence intervals (CI) ranging between - 1.0 and - 5.0) reduced at all time points when compared to the baseline. Besides the pure pain levels, the presented data also provide detailed insights into the complex associated issues the patient collective is facing including impairment in everyday life, fitness for work and leisure time activities. These parameters were also substantially improved (95% CI between - 0.0 and - 5.0) at all time points indicating a comprehensive patient benefit. Self-reported patient satisfaction, recommendation of the procedure and personal success were rated high (62-100%). The rate of patients on sick leave dropped from 23.7 to 1.9%. Accordingly, patients reported a high rate of satisfaction with the procedures. There was a high technical and clinical success rate with no major complications.

Conclusion: CT-guided pain therapy on the lumbar spine is effective and safe with a comprehensive benefit for patients, including not only pain levels in the narrow meaning but also regarding everyday life, fitness for work and leisure time activities at all investigated time points including 3 months follow-up.

计算机断层扫描引导下神经根周围浸润和小关节浸润的多中心前瞻性研究。
目的:评价多中心前瞻性椎弓根周围浸润和小关节浸润的成功率。材料和方法:114例因第一腰椎节段和第一骶节段之间的神经根和/或小关节症状而接受神经根或小关节浸润治疗的患者在德国的9个参与研究中心前瞻性和连续入组。这些中心在96个月的时间里持续提供ct引导的疼痛治疗。评估是通过系统的患者调查进行的,包括疼痛问卷。疼痛的严重程度和疼痛引起的损害采用11点数值评定量表进行评估。结果:ct引导下的神经根周围浸润和关节突关节浸润在所有时间点和最后一次干预后3个月内显著降低了疼痛水平和疼痛频率。与基线相比,所有疼痛相关特征(即实际疼痛、平均疼痛水平、最大疼痛水平)在所有时间点均显著降低(95%置信区间(CI)在- 1.0至- 5.0之间)。除了单纯的疼痛水平外,所呈现的数据还提供了对患者集体面临的复杂相关问题的详细见解,包括日常生活,工作和休闲活动的损害。在所有时间点,这些参数也得到了显著改善(95% CI在- 0.0和- 5.0之间),表明患者全面受益。患者自我报告的满意度、手术推荐率和个人成功率均较高(62% -100%)。病人请病假的比率从23.7%下降到1.9%。因此,患者对手术的满意度很高。技术和临床成功率高,无重大并发症。结论:ct引导下的腰椎疼痛治疗是有效、安全的,对患者的益处是全面的,不仅包括狭义的疼痛水平,而且包括在包括3个月随访在内的所有调查时间点的日常生活、工作健身和休闲活动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Neuroradiology
Neuroradiology 医学-核医学
CiteScore
5.30
自引率
3.60%
发文量
214
审稿时长
4-8 weeks
期刊介绍: Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.
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