Impact of vaccines on antimicrobial resistance.

IF 2
Gordon Dougan, Emily Hugo-Webb
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Abstract

Antimicrobial resistance (AMR) is a real and current threat to public health, yet the role of vaccines in combating this crisis remains underutilized and under-recognized. This meeting report summarizes key insights from a multidisciplinary workshop convened by the Microbiology Society in February 2025, as part of the Knocking Out AMR initiative, bringing together 21 expert stakeholders across academia, industry, clinical and veterinary sectors and policy. The workshop explored how vaccines can reduce the burden of AMR by preventing infections, limiting antibiotic use and slowing resistance development. Discussions highlighted the need to strengthen the evidence base for vaccine-mediated AMR reduction, address policy and regulatory barriers and incentivize public-private collaboration in vaccine development. Participants called for AMR impact to be formally recognized in vaccine labelling and national immunization strategies, and for greater integration of vaccines into AMR action plans. The workshop also underscored the importance of One Health approaches, investment in research for both human and animal vaccines and the role of the microbiology community in driving change.

疫苗对抗菌素耐药性的影响。
抗微生物药物耐药性(AMR)是对公共卫生的现实和当前威胁,但疫苗在应对这一危机中的作用仍未得到充分利用和认识。本会议报告总结了微生物学会于2025年2月召开的多学科研讨会的主要见解,该研讨会是“消灭AMR”倡议的一部分,汇集了来自学术界、工业界、临床和兽医部门以及政策部门的21名专家利益相关者。讲习班探讨了疫苗如何通过预防感染、限制抗生素使用和减缓耐药性的发展来减轻抗菌素耐药性的负担。讨论强调需要加强疫苗介导的抗菌素耐药性减少的证据基础,解决政策和监管障碍,并鼓励在疫苗开发方面进行公私合作。与会者呼吁在疫苗标签和国家免疫战略中正式承认抗菌素耐药性的影响,并呼吁将疫苗更多地纳入抗菌素耐药性行动计划。讲习班还强调了“同一个健康”方针的重要性、对人类和动物疫苗研究的投资以及微生物界在推动变革方面的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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