Prevalence, Risk Factors and Outcomes of Rhegmatogenous Retinal Detachments Repair in Marfan syndrome.

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-08-12 DOI:10.1097/IAE.0000000000004643

Ahmed A Nagshbandi, Moustafa S Magliyah, Abdulrahman F Algwaiz, Abdulmajeed I Alhaidari, Ahmed B Sallam, Abdulrahman H Badawi

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引用次数: 0

Abstract

Purpose: To report the prevalence, risk factors, and surgical management outcomes of rhegmatogenous retinal detachment (RRD) in Marfan Syndrome.

Methods: Retrospective chart review of 82 patients with Marfan Syndrome who have developed RRD. The collected data included lens status, previous surgeries, details of intraoperative retinal findings and follow up outcomes.

Results: The study included 163 eyes of 82 patients. Forty-three patients (52.4%) were males. The mean duration of follow ups was 15.3 ± 13.4 years. RRD occurred in 54 eyes (33.1%). The mean age at the time of RRD was 25.2 ±12.5 years. Risk of RRD was significantly higher among patients who had prior trauma (P=0.014), previous ocular surgery (P=0.001), lensectomy without implantation of an intraocular lens (P=0.002) aphakia (P<0.001), lens subluxation (P=0.002) and higher axial length (P<0.001). Successful primary reattachment was achieved in 36 eyes (69.2%) while 16 eyes (30.8%) required secondary repairs to achieve reattachments.

Conclusions: Eyes with Marfan Syndrome have a 33.1% risk of developing RRD upon long-term follow ups. Prior trauma, intraocular surgeries, aphakic status and high axial length are associated with higher risk. High reattachments rates could be achieved after surgical repairs.

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马凡氏综合征中孔源性视网膜脱离修复的患病率、危险因素和结局。

目的：报道马凡氏综合征中孔源性视网膜脱离（RRD）的患病率、危险因素和手术治疗结果。方法：回顾性分析82例马凡氏综合征并发RRD的病例。收集的数据包括晶状体状态、既往手术、术中视网膜发现的细节和随访结果。结果：共纳入82例患者163只眼。男性43例（52.4%）。平均随访时间15.3±13.4年。RRD 54眼（33.1%）。RRD时的平均年龄为25.2±12.5岁。有外伤（P=0.014）、眼部手术（P=0.001）、晶状体切除术未植入人工晶状体（P=0.002）、无晶状体的患者发生RRD的风险显著高于无晶状体患者（P=0.002）。结论：长期随访马凡综合征患者发生RRD的风险为33.1%。既往创伤、眼内手术、无晶状体状态和高眼轴长度与较高的风险相关。手术修复后可获得较高的再附着率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.