Saaniya Farhan, Laura A Colangelo, Abigail Marie Gauen, Nilay S Shah, Alka M Kanaya, Kiarri N Kershaw, Michael P Bancks, Sameera Talegawkar, Luis A Rodriguez, Donald M Lloyd-Jones, Norrina B Allen, Rachel Zmora
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引用次数: 0
Abstract
Introduction: Research suggests chronic stress is associated with individual cardiovascular health (CVH) metrics (e.g., physical activity and diet quality); however, the association between chronic stress and overall CVH is less well understood. Further, minoritized racial and ethnic groups experience a disproportionate stress burden. Therefore, this study assessed the association between chronic stress and CVH within two racially and ethnically diverse cohorts.
Methods: This study utilized pooled data from 7978 participants of the Multi-Ethnic Study of Atherosclerosis (MESA) and the Mediators of Atherosclerosis in South Asians Living in America (MASALA) studies collected between 2000-2011 and 2010-2018, respectively. The associations between chronic stress and the cross-sectional and annualized change in Life's Essential Eight CVH score, excluding sleep, (range 0-100), were assessed using linear regression to adjust for sociodemographic factors. Anxiety, depression, and social support were assessed as potential moderators of this association. Analyses were repeated using individual CVH metrics as the outcome. Analyses were conducted in 2025.
Results: In cross-sectional analyses, individuals with high chronic stress had a 2.7-point lower (-2.71, 95% CI = -3.46, -1.95) CVH score compared to individuals with no chronic stress after adjustment. No association between chronic stress and annualized change in CVH score was observed. Additionally, there was no moderation by anxiety, depression, or social support.
Conclusions: Elevated chronic stress is adversely associated with concurrent CVH. These results highlight the important relationship between chronic stress and health.
研究表明,慢性压力与个体心血管健康(CVH)指标(例如,身体活动和饮食质量)有关;然而,慢性压力与整体CVH之间的关系尚不清楚。此外,少数种族和族裔群体承受着不成比例的压力负担。因此,本研究在两个种族和民族多样化的队列中评估了慢性应激与CVH之间的关系。方法:本研究分别收集了2000-2011年和2010-2018年在美国生活的南亚人的多种族动脉粥样硬化研究(MESA)和动脉粥样硬化介质研究(MASALA)的7978名参与者的汇总数据。慢性压力与生活基本8 CVH评分(不包括睡眠)的横截面和年化变化(范围0-100)之间的关系,使用线性回归来调整社会人口因素。焦虑、抑郁和社会支持被评估为这种关联的潜在调节因子。使用个别CVH指标作为结果重复分析。分析在2025年进行。结果:在横断面分析中,调整后慢性压力高的个体CVH评分比没有慢性压力的个体低2.7点(-2.71,95% CI = -3.46,-1.95)。慢性应激与CVH评分年化变化之间无关联。此外,焦虑、抑郁或社会支持也没有缓和。结论:慢性应激升高与并发CVH呈负相关。这些结果强调了慢性压力与健康之间的重要关系。
期刊介绍:
The American Journal of Preventive Medicine is the official journal of the American College of Preventive Medicine and the Association for Prevention Teaching and Research. It publishes articles in the areas of prevention research, teaching, practice and policy. Original research is published on interventions aimed at the prevention of chronic and acute disease and the promotion of individual and community health.
Of particular emphasis are papers that address the primary and secondary prevention of important clinical, behavioral and public health issues such as injury and violence, infectious disease, women''s health, smoking, sedentary behaviors and physical activity, nutrition, diabetes, obesity, and substance use disorders. Papers also address educational initiatives aimed at improving the ability of health professionals to provide effective clinical prevention and public health services. Papers on health services research pertinent to prevention and public health are also published. The journal also publishes official policy statements from the two co-sponsoring organizations, review articles, media reviews, and editorials. Finally, the journal periodically publishes supplements and special theme issues devoted to areas of current interest to the prevention community.