Internet-Based Behavioral Cough Suppression Therapy for Refractory Chronic Cough: A Randomized Controlled Trial.

IF 2.5 3区 医学 Q1 AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY
Jane R Salois, Kassidi L Heinle, Laurie J Slovarp, Marie E Jetté, Vinaya Manchaiah, George Vlaescu, Gerhard Andersson
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引用次数: 0

Abstract

Purpose: The purpose of this study was to assess the efficacy of internet-based behavioral cough suppression therapy (IBCST) and explore users' experiences.

Method: This study involved a prospective, single-blind, randomized controlled trial comparing the efficacy of a 5-week IBCST and healthy lifestyle education control intervention in patients with refractory chronic cough. Additionally, qualitative interviews were conducted and analyzed using grounded theory methodology.

Interventions: IBCST and the healthy lifestyle control included 5 weeks of asynchronous content delivered via video and text on a study-specific website. IBCST emphasized education and cough suppression.

Outcomes: The Leicester Cough Questionnaire (LCQ) and Cough Severity Visual Analog Scale (VAS) were the primary and secondary outcome measures, respectively, and were administered at baseline (T0), 1-week posttreatment (T1), and 1-month posttreatment (T2). Semistructured qualitative interviews were conducted with a subgroup of IBCST participants.

Results: Thirty-nine adults with refractory chronic cough enrolled, and 30 (27 women, three men; Mage = 61 years) completed the study (18 IBCST, 12 control). IBCST resulted in clinically significant improvements for 72% of participants in LCQ total score at T1 with a mean change of 3.74 (p = .014, ηp2 = .205) and 76% of participants at T2 with a mean change of 4.1 (p = .033, ηp2 = .163). VAS changes did not reach the minimum clinically meaningful threshold but trended in that direction for the IBCST group at T1 (p = .056, ηp2 = .128). Qualitative analysis revealed IBCST participants liked the convenience and quality of treatment and experienced improvements in symptom control.

Conclusion: IBCST was feasible and efficacious and resulted in total LCQ score changes on par with what has been reported for other BCST interventions, paving the way for adaptation to a digital therapeutic.

基于互联网的行为止咳治疗难治性慢性咳嗽:一项随机对照试验。
目的:本研究的目的是评估基于网络的行为止咳疗法(IBCST)的疗效,并探讨用户体验。方法:本研究采用前瞻性、单盲、随机对照试验,比较5周IBCST和健康生活方式教育控制干预对难治性慢性咳嗽患者的疗效。此外,定性访谈进行和分析使用扎根理论的方法。干预措施:IBCST和健康生活方式控制包括在研究特定网站上通过视频和文本提供5周的异步内容。IBCST强调教育和咳嗽抑制。结果:莱斯特咳嗽问卷(LCQ)和咳嗽严重程度视觉模拟量表(VAS)分别是主要和次要的结果测量指标,分别在基线(T0)、治疗后1周(T1)和治疗后1个月(T2)进行。对IBCST参与者的一个亚组进行了半结构化定性访谈。结果:纳入39例成人难治性慢性咳嗽患者,30例(女性27例,男性3例;患者(61岁)完成研究(18例IBCST, 12例对照组)。IBCST使72%的受试者在T1时LCQ总分有显著改善,平均变化3.74 (p = 0.014, ηp2 = 0.205), 76%的受试者在T2时LCQ总分有显著改善,平均变化4.1 (p = 0.033, ηp2 = 0.163)。VAS变化未达到最低临床意义阈值,但IBCST组在T1时趋向于该方向(p = 0.056, ηp2 = 0.128)。定性分析显示IBCST参与者喜欢治疗的便利性和质量,并在症状控制方面有所改善。结论:IBCST是可行和有效的,导致LCQ总分的变化与其他BCST干预措施相同,为适应数字化治疗铺平了道路。
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来源期刊
American Journal of Speech-Language Pathology
American Journal of Speech-Language Pathology AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY-REHABILITATION
CiteScore
4.30
自引率
11.50%
发文量
353
审稿时长
>12 weeks
期刊介绍: Mission: AJSLP publishes peer-reviewed research and other scholarly articles on all aspects of clinical practice in speech-language pathology. The journal is an international outlet for clinical research pertaining to screening, detection, diagnosis, management, and outcomes of communication and swallowing disorders across the lifespan as well as the etiologies and characteristics of these disorders. Because of its clinical orientation, the journal disseminates research findings applicable to diverse aspects of clinical practice in speech-language pathology. AJSLP seeks to advance evidence-based practice by disseminating the results of new studies as well as providing a forum for critical reviews and meta-analyses of previously published work. Scope: The broad field of speech-language pathology, including aphasia; apraxia of speech and childhood apraxia of speech; aural rehabilitation; augmentative and alternative communication; cognitive impairment; craniofacial disorders; dysarthria; fluency disorders; language disorders in children; speech sound disorders; swallowing, dysphagia, and feeding disorders; and voice disorders.
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