{"title":"The association between dietary obesity-prevention score and cardiovascular risk factors.","authors":"Zahra Salehi, Batoul Ghosn, Azadeh Aminianfar, Hamidreza Pouragha, Leila Azadbakht","doi":"10.1186/s40795-025-01141-y","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>The Dietary Obesity Prevention Score (DOS) is a dietary assessment tool previously linked to obesity. This study aimed to explore the association between DOS and selected cardiovascular disease (CVD) risk factors.</p><p><strong>Design: </strong>A cross-sectional analysis was conducted among 1,332 adult employees of Tehran University of Medical Sciences. Dietary intake was assessed using a validated food frequency questionnaire (FFQ), and DOS was calculated based on established criteria. Serum levels of total cholesterol, low-density lipoprotein cholesterol) LDL-C(, high-density lipoprotein cholesterol (HDL-C), triglyceride (TG) and blood sugar (BS) levels were measured using standard commercial kits. Binary logistic regression models were used to examine the association between DOS and CVD risk factors.</p><p><strong>Setting: </strong>Tehran University of Medical Sciences.</p><p><strong>Participants: </strong>One thousand three hundred thirty-two adults university employees.</p><p><strong>Results: </strong>The mean age and body mass index (BMI) of participants were 42.8 years and 27.2 kg/m<sup>2</sup>, respectively. After adjusting for potential confounders, individuals in the highest DOS quintile had 47% lower odds of hypertension compared to those in the lowest quintile (OR: 0.53; 95% CI: 0.30-0.94; P = 0.006). A marginally significant inverse association was also observed for low HDL-C (OR: 0.60; 95% CI: 0.38-0.95; P = 0.05). No significant associations were found between DOS and other CVD risk factors.</p><p><strong>Conclusions: </strong>Higher adherence to the Dietary Obesity Prevention Score may be linked to lower odds of hypertension and low HDL-C. Further research is warranted to confirm these findings.</p>","PeriodicalId":36422,"journal":{"name":"BMC Nutrition","volume":"11 1","pages":"165"},"PeriodicalIF":2.2000,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12351968/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Nutrition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s40795-025-01141-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: The Dietary Obesity Prevention Score (DOS) is a dietary assessment tool previously linked to obesity. This study aimed to explore the association between DOS and selected cardiovascular disease (CVD) risk factors.
Design: A cross-sectional analysis was conducted among 1,332 adult employees of Tehran University of Medical Sciences. Dietary intake was assessed using a validated food frequency questionnaire (FFQ), and DOS was calculated based on established criteria. Serum levels of total cholesterol, low-density lipoprotein cholesterol) LDL-C(, high-density lipoprotein cholesterol (HDL-C), triglyceride (TG) and blood sugar (BS) levels were measured using standard commercial kits. Binary logistic regression models were used to examine the association between DOS and CVD risk factors.
Setting: Tehran University of Medical Sciences.
Participants: One thousand three hundred thirty-two adults university employees.
Results: The mean age and body mass index (BMI) of participants were 42.8 years and 27.2 kg/m2, respectively. After adjusting for potential confounders, individuals in the highest DOS quintile had 47% lower odds of hypertension compared to those in the lowest quintile (OR: 0.53; 95% CI: 0.30-0.94; P = 0.006). A marginally significant inverse association was also observed for low HDL-C (OR: 0.60; 95% CI: 0.38-0.95; P = 0.05). No significant associations were found between DOS and other CVD risk factors.
Conclusions: Higher adherence to the Dietary Obesity Prevention Score may be linked to lower odds of hypertension and low HDL-C. Further research is warranted to confirm these findings.