Christopher J Morris, Erin Jenewein, Mitchell Scheiman, Tara L Alvarez
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引用次数: 0
Abstract
Purpose: Intermittent exotropia (IXT) control is challenging to assess clinically because of the variability inherent to this condition. The Binocular Eye Alignment Monitor (BEAM) is a proof-of-concept device that extends eye alignment monitoring for use at home. This study seeks to determine whether the BEAM is feasible for continuously monitoring eye position to identify differences between participants with normal binocular vision and those with IXT.
Methods: An eye tracking system integrated with a custom controller was engineered to measure the magnitude and duration of exodeviation for up to four hours. Twelve participants (six diagnosed with IXT and six with normal binocular vision) completed two separate recordings alongside a clinical sensory motor examination.
Results: The BEAM successfully recorded eye alignment for 90 minutes and demonstrated that IXT participants exhibited significantly greater ocular misalignment than participants with normal binocular vision.
Conclusions: The BEAM is feasible for assessing the magnitude and frequency of temporal exodeviation in the IXT population over prolonged periods while watching a movie from a distance of 6 m, with the participant seated.
Translational relevance: At-home monitoring to evaluate ocular exodeviation for intermittent exotropic patients is feasible with the BEAM. The BEAM's measurements have the potential to provide objective diagnostic criteria and baseline and outcome assessments for studying the effectiveness of therapeutic interventions in the IXT population.
期刊介绍:
Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO.
The journal covers a broad spectrum of work, including but not limited to:
Applications of stem cell technology for regenerative medicine,
Development of new animal models of human diseases,
Tissue bioengineering,
Chemical engineering to improve virus-based gene delivery,
Nanotechnology for drug delivery,
Design and synthesis of artificial extracellular matrices,
Development of a true microsurgical operating environment,
Refining data analysis algorithms to improve in vivo imaging technology,
Results of Phase 1 clinical trials,
Reverse translational ("bedside to bench") research.
TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.