Binocular Eye Alignment Monitor (BEAM): Home Monitoring Proof-of-Concept Device to Quantify Binocular Alignment for Intermittent Exotropia.

IF 2.6 3区 医学 Q2 OPHTHALMOLOGY
Christopher J Morris, Erin Jenewein, Mitchell Scheiman, Tara L Alvarez
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Abstract

Purpose: Intermittent exotropia (IXT) control is challenging to assess clinically because of the variability inherent to this condition. The Binocular Eye Alignment Monitor (BEAM) is a proof-of-concept device that extends eye alignment monitoring for use at home. This study seeks to determine whether the BEAM is feasible for continuously monitoring eye position to identify differences between participants with normal binocular vision and those with IXT.

Methods: An eye tracking system integrated with a custom controller was engineered to measure the magnitude and duration of exodeviation for up to four hours. Twelve participants (six diagnosed with IXT and six with normal binocular vision) completed two separate recordings alongside a clinical sensory motor examination.

Results: The BEAM successfully recorded eye alignment for 90 minutes and demonstrated that IXT participants exhibited significantly greater ocular misalignment than participants with normal binocular vision.

Conclusions: The BEAM is feasible for assessing the magnitude and frequency of temporal exodeviation in the IXT population over prolonged periods while watching a movie from a distance of 6 m, with the participant seated.

Translational relevance: At-home monitoring to evaluate ocular exodeviation for intermittent exotropic patients is feasible with the BEAM. The BEAM's measurements have the potential to provide objective diagnostic criteria and baseline and outcome assessments for studying the effectiveness of therapeutic interventions in the IXT population.

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双目眼睛对准监测器(BEAM):用于量化间歇性外斜视双眼对准的家庭监测概念验证装置。
目的:间歇性外斜视(IXT)控制是具有挑战性的临床评估,因为这种情况固有的可变性。双目眼睛对准监视器(BEAM)是一种概念验证设备,扩展了家庭使用的眼睛对准监测。本研究旨在确定BEAM是否可用于连续监测眼睛位置,以识别双眼视力正常的参与者与IXT参与者之间的差异。方法:设计了一个眼动追踪系统,集成了一个定制控制器来测量外移的大小和持续时间,最长可达4小时。12名参与者(6名诊断为IXT, 6名双眼视力正常)在临床感觉运动检查的同时完成了两次单独的记录。结果:BEAM成功地记录了90分钟的眼睛对准,并证明了IXT参与者比双眼视力正常的参与者表现出更大的眼睛不对准。结论:BEAM可用于评估IXT人群在长时间观看6米远的电影时时间外偏移的幅度和频率。翻译相关性:家用BEAM监测间歇性外斜视患者的眼外斜视是可行的。BEAM的测量有可能为研究IXT人群治疗干预的有效性提供客观的诊断标准、基线和结果评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Translational Vision Science & Technology
Translational Vision Science & Technology Engineering-Biomedical Engineering
CiteScore
5.70
自引率
3.30%
发文量
346
审稿时长
25 weeks
期刊介绍: Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO. The journal covers a broad spectrum of work, including but not limited to: Applications of stem cell technology for regenerative medicine, Development of new animal models of human diseases, Tissue bioengineering, Chemical engineering to improve virus-based gene delivery, Nanotechnology for drug delivery, Design and synthesis of artificial extracellular matrices, Development of a true microsurgical operating environment, Refining data analysis algorithms to improve in vivo imaging technology, Results of Phase 1 clinical trials, Reverse translational ("bedside to bench") research. TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.
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