Effect of cranial electro-stimulation on cognition in perimenopausal women: randomized control study.

IF 3.2 4区医学 Q1 OBSTETRICS & GYNECOLOGY

Climacteric Pub Date : 2025-08-14 DOI:10.1080/13697137.2025.2530444

Naveeta Thakur, Nidhi Sharma, Simranjeet Kaur, Parveen Kumar, Preeti Kapri, Priyanka Negi

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引用次数: 0

Abstract

Objective: The aim of this study was to investigate the efficacy of cranial electrotherapy stimulation (CES) on cognition among perimenopausal women.

Methods: The pretest-post-test randomized controlled trial was conducted between April 2024 and January 2025. Forty-six perimenopausal women, aged 40-55 years, were randomized into two groups: active CES (n = 23) or sham CES (n = 23). Participants were blinded to the study. Both groups received 30-min sessions, 4 days a week for 4 weeks. The participants were assessed at baseline and at the end of 4 weeks of intervention using the Montreal Cognitive Assessment (MoCA) scale.

Results: Demographic and baseline characteristics depicted a normal distribution for both groups, except for MoCA (p < 0.05). Within-group analyses of both groups demonstrated significant differences for MoCA (active CES, p = 0.001; sham CES, p = 0.002) with large effect size ≥ 0.5. Between-group analyses of MoCA showed no significant difference with p = 0.212 and small effect size ≤ 0.3. The time and group interaction effect showed significant improvement with p = 0.001.

Conclusions: CES has the potential to enhance cognitive function in perimenopausal women. Additionally, no adverse events related to the study were reported.

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颅电刺激对围绝经期妇女认知能力的影响：随机对照研究。

目的：探讨颅电刺激对围绝经期妇女认知功能的影响。方法：于2024年4月~ 2025年1月进行前-后随机对照试验。46名40-55岁围绝经期妇女随机分为两组：活动性CES （n = 23）和假性CES （n = 23）。参与者对这项研究是不知情的。两组均接受30分钟的治疗，每周4天，持续4周。参与者在基线和干预4周结束时使用蒙特利尔认知评估（MoCA）量表进行评估。结果：两组的人口统计学和基线特征均为正态分布，但MoCA除外(p p = 0.001；sham CES, p = 0.002)，大效应量≥0.5。MoCA组间分析无显著差异（p = 0.212），效应量小（≤0.3）。时间和组间相互作用效果有显著改善（p = 0.001）。结论：CES有增强围绝经期妇女认知功能的潜力。此外，没有与研究相关的不良事件的报道。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Climacteric 医学-妇产科学

CiteScore

1.70

自引率

7.10%

发文量

审稿时长

1 months

期刊介绍： Climacteric is the official journal of the International Menopause Society (IMS). As an international peer-reviewed journal it publishes original research and reviews of all aspects of aging in women. Climacteric was founded by the IMS in 1998 and today has become a leading journal in the publication of peer-reviewed papers on the menopause, climacteric and mid-life health. Topics covered include endocrine changes, symptoms attributed to the menopause and their treatment, hormone replacement and alternative therapies, lifestyles, and the counselling and education of peri- and postmenopausal women. Climacteric, published bimonthly, also features regular invited reviews, editorials and commentaries on recent developments. The editorial review board of Climacteric includes leading scientific and clinical experts in the field of midlife medicine and research and is headed by its Editor-in-Chief, Professor Rod Baber of Australia. He and his team of Associate Editors act independently to set a clear editorial policy, co-ordinate peer review, and ensure a rapid response to submitted papers.