Synthesis of a naphthalimide-functionalized polymethacrylate: a turn-on fluorescent probe for sulfinic acids via covalent bond formation

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-08-04 DOI:10.1039/d5ob00967g

Hiroki Tanimoto , Aoi Otsuki , Takenori Tomohiro

引用次数: 0

Abstract

A fluorescent naphthalimide azocarboxylate was successfully tethered to a polymethacrylate backbone. The resulting polymeric material exhibits efficient turn-on fluorescence upon sulfinate addition onto the azo moiety forming covalent bonding, with minimal quenching effects from non-emissive isomeric units, demonstrating its potential for developing fluorescent labelling for sulfinated-proteins.

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萘酰亚胺功能化聚甲基丙烯酸酯的合成：通过共价键形成亚磺酸的开启荧光探针。

荧光萘酰亚胺偶氮羧酸酯成功地拴在聚甲基丙烯酸酯骨架上。所得聚合物材料在亚硫酸盐加成到偶氮部分形成共价键时显示出有效的开启荧光，而非发射异构体单元的猝灭效应最小，表明其在亚硫酸盐蛋白质荧光标记方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.