SPR-Enhanced Detection of Isopropanol Vapor Using Au/MIP-Coated Optical Fiber Sensor

IF 4.3 2区综合性期刊 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC

IEEE Sensors Journal Pub Date : 2025-07-10 DOI:10.1109/JSEN.2025.3585846

Akhilesh Kumar Pathak;Kankan Swargiary;Charusluk Viphavakit

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Abstract

Isopropanol (IPA) is a common volatile organic compound (VOC) linked to lung cancer. This study presents an experimental validation of a highly sensitive and selective method for detecting IPA vapor. The method employs a molecularly imprinted polymer (MIP) functionalized on a thin gold (Au) film, which is coated over a small section of no-core fiber (NCF). The sensitivity of the MIP-coated sensor with surface plasmon resonance (SPR) facilitated by the thin gold layer is experimentally compared with the MIP-coated bare NCF. The fabricated sensors were tested with various VOCs, including acetone, methanol, ethanol, and IPA, to evaluate their selectivity. The sensors demonstrated selective detection of IPA at parts per million (ppm) levels at room temperature. Our results show that the Au/MIP sensor exhibits seven times higher sensitivity (0.014 nm/ppm) compared to the bare fiber coated only with the MIP layer (0.002 nm/ppm), along with a limit of detection (LOD) of 82.41 ppm. Control experiments suggest that the combined effect of the MIP and the gold film significantly enhances the performance of the optical fiber sensor. These findings highlight the potential of this sensor for noninvasive exhaled breath measurement of VOC biomarkers.

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利用Au/ mip包覆光纤传感器对异丙醇蒸汽进行spr增强检测

异丙醇（IPA）是一种常见的挥发性有机化合物（VOC），与肺癌有关。本研究提出了一种高灵敏度、高选择性的检测IPA蒸汽的方法。该方法将分子印迹聚合物（MIP）功能化在薄金（Au）薄膜上，并将其涂覆在一小段无芯光纤（NCF）上。实验比较了薄金层促进表面等离子体共振（SPR）的mip包覆传感器与裸NCF包覆mip的灵敏度。用丙酮、甲醇、乙醇和异丙醇等多种挥发性有机化合物对传感器进行了选择性测试。这些传感器在室温下可选择性地检测百万分之一（ppm）的IPA。我们的研究结果表明，Au/MIP传感器的灵敏度（0.014 nm/ppm）比仅涂有MIP层的裸光纤（0.002 nm/ppm）高7倍，检测限（LOD）为82.41 ppm。控制实验表明，MIP和金膜的共同作用显著提高了光纤传感器的性能。这些发现突出了该传感器在无创呼气测量VOC生物标志物方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Sensors Journal 工程技术-工程：电子与电气

CiteScore

7.70

自引率

14.00%

发文量

2058

审稿时长

5.2 months

期刊介绍： The fields of interest of the IEEE Sensors Journal are the theory, design , fabrication, manufacturing and applications of devices for sensing and transducing physical, chemical and biological phenomena, with emphasis on the electronics and physics aspect of sensors and integrated sensors-actuators. IEEE Sensors Journal deals with the following: -Sensor Phenomenology, Modelling, and Evaluation -Sensor Materials, Processing, and Fabrication -Chemical and Gas Sensors -Microfluidics and Biosensors -Optical Sensors -Physical Sensors: Temperature, Mechanical, Magnetic, and others -Acoustic and Ultrasonic Sensors -Sensor Packaging -Sensor Networks -Sensor Applications -Sensor Systems: Signals, Processing, and Interfaces -Actuators and Sensor Power Systems -Sensor Signal Processing for high precision and stability (amplification, filtering, linearization, modulation/demodulation) and under harsh conditions (EMC, radiation, humidity, temperature); energy consumption/harvesting -Sensor Data Processing (soft computing with sensor data, e.g., pattern recognition, machine learning, evolutionary computation; sensor data fusion, processing of wave e.g., electromagnetic and acoustic; and non-wave, e.g., chemical, gravity, particle, thermal, radiative and non-radiative sensor data, detection, estimation and classification based on sensor data) -Sensors in Industrial Practice