Repeatability and reproducibility of anterior segment measurements with a new full-range SS-OCT and comparison with an AS-OCT

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-08-11 DOI:10.1016/j.pdpdt.2025.104763

Chak Seng Lei , Xinyu Jiang , Xinning Yang , Qing Wang , Kexin Li , Rui Ning , Giacomo Savini , Domenico Schiano-Lomoriello , Xingtao Zhou , Jinhai Huang

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引用次数: 0

Abstract

Purpose

To evaluate the intraobserver repeatability and interobserver reproducibility of anterior segment parameters measured by the new YG-100K full-range swept-source optical coherence tomographer (SS-OCT) and compare them with values from the validated CASIA 2 anterior segment optical coherence tomographer (AS-OCT).

Methods

In a randomized sequence, the first operator conducted three consecutive measurements with both devices, while a second operator independently conducted three consecutive measurements with only the YG-100K. Each device’s built-in software automatically identified the scleral spur and angle recess. Measured parameters included central corneal thickness (CCT), anterior chamber depth (ACD), angle-to-angle (ATA) distance, anterior chamber width (ACW), lens vault (LV), crystalline lens rise (CLR), lens thickness (LT), trabecular iris angle (TIA), angle open distance (AOD) and trabecular iris space area (TISA). The within-subject standard deviation (Sw), test-retest (TRT) repeatability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated. Bland-Altman plots were assessed inter-device agreement.

Results

The YG-100K demonstrated excellent repeatability and reproducibility, evidenced by low Sw, TRT, and CoV values, and ICCs nearing 1.000 (intraobserver ICCs: 0.918−0.998; interobserver ICCs: 0.972−0.998). Comparative analysis revealed good agreement for CCT and ACD. However, ATA and ACW were significantly lower, whereas LT, LV and CLR were slightly higher with YG-100K. Angle measurements between the two devices showed wide 95 % limits of agreement (LoA).

Conclusions

This new full-range SS-OCT exhibited high repeatability and reproducibility for anterior segment measurements, confirming its reliability. However, significant differences and wide 95 % LoAs compared to the CASIA 2 suggested that these devices were not interchangeable.

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新型全范围SS-OCT前段测量的可重复性和再现性及其与AS-OCT的比较。

目的：评价新型YG-100K全范围扫源光学相干层析仪（SS-OCT）测量的前段参数在观察者内的可重复性和观察者间的可重复性，并将其与经过验证的CASIA 2前段光学相干层析仪（AS-OCT）的值进行比较。方法：按随机顺序，第一名操作员使用两种设备连续进行三次测量，第二名操作员单独使用YG-100K连续进行三次测量。每个设备的内置软件自动识别巩膜骨刺和角隐窝。测量参数包括角膜中央厚度（CCT）、前房深度（ACD）、角对角距离（ATA）、前房宽度（ACW）、晶状体穹窿（LV）、晶状体上升（CLR）、晶状体厚度（LT）、虹膜小梁角（TIA）、角开距（AOD）和虹膜小梁间隙面积（TISA）。计算受试者内标准差（Sw）、重测重复性（TRT）、变异系数（CoV）和类内相关系数（ICC）。Bland-Altman图评估设备间一致性。结果：YG-100K具有良好的重复性和再现性，具有较低的Sw、TRT和CoV值，ICCs接近1.000(观察者内ICCs为0.918-0.998；观察者间icc: 0.972-0.998)。对比分析显示CCT与ACD具有较好的一致性。但ATA和ACW明显降低，而LT、LV和CLR略高于YG-100K。两个装置之间的角度测量显示95%的一致性限制（LoA）。结论：这种新的全范围SS-OCT对前节测量具有高重复性和再现性，证实了其可靠性。然而，与CASIA 2相比，显着差异和95%的LoAs宽表明这些装置不可互换。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.