Intensity modifies the association between continuous bouts of physical activity and risk of mortality: A prospective UK Biobank cohort analysis.

IF 10.3 1区医学 Q1 HOSPITALITY, LEISURE, SPORT & TOURISM

Journal of Sport and Health Science Pub Date : 2025-08-11 DOI:10.1016/j.jshs.2025.101078

Alex V Rowlands, Fabian Schwendinger, Cameron Razieh, Joe Henson, Jonathan Goldney, Andrew P Kingsnorth, Melanie Davies, Kamlesh Khunti, Francesco Zaccardi, Tom Yates

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引用次数: 0

Abstract

Background: Recent evidence suggests continuous bouts of physical activity (PA) are associated with longevity. We hypothesized the risk of mortality would be lower when the most active minutes of the day were in a continuous bout.

Methods: PA was assessed using accelerometery in UK Biobank participants. The intensity of the most active continuous (MX_CONT) and accumulated (MX) X min of the day, and their ratio (MX_RATIO = MX_CONT/MX), were determined. MX_RATIO indicates how the most active minutes of the day are accumulated, ranging from a single continuous bout through to sporadic accumulation spread across the day. Durations (X) considered ranged from 1 to 20 min. The outcome was mortality.

Results: In total, 94,541 participants (56.5% female) were included. Over a median (interquartile range) follow-up of 6.9 (6.3,7.4) years, 2649 (2.8%) deaths occurred. Intensity moderated the association between how the most active minutes of the day were accumulated and mortality risk, expressed relative to sporadically accumulated moderate PA. If the most active minutes were of moderate intensity, the risk of mortality was halved for continuous compared to sporadic accumulation, irrespective of duration; if the most active minutes were of vigorous intensity, a continuous bout was associated with the lowest risk for durations under 5 min (e.g., 3 min: hazard ratio [HR] = 0.27, [95%confidence interval {95%CI}: 0.21-0.34]), while sporadic accumulation was associated with the lowest risk for durations beyond 5 min (HR = 0.11,[95%CI: 0.08-0.15] for the most active 20 min).

Conclusion: Optimal PA patterns for reducing mortality differ by intensity and duration. For moderate-intensity PA, a lower mortality risk may be optimized by prioritizing continuous PA for up to 20 min. However, for vigorous-intensity PA, multiple short bouts (< 5 min) may be optimal. This suggests tailored PA recommendations may enhance longevity benefits.

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强度改变了连续运动与死亡风险之间的关系：一项前瞻性英国生物银行队列分析。

背景：最近的证据表明，持续的身体活动（PA）与长寿有关。我们假设，当一天中最活跃的几分钟持续发作时，死亡风险会降低。方法：使用加速度计评估英国生物银行参与者的PA。测定一天中最活跃连续（MXCONT）和累积（MX） X min的强度及其比值（MXRATIO = MXCONT/MX）。MXRATIO显示了一天中最活跃的几分钟是如何积累起来的，范围从单一的连续回合到分散在一天中的零星积累。考虑的持续时间(X)从1到20分钟不等。结果是死亡率。结果：共纳入94,541名参与者，其中56.5%为女性。在中位（四分位数范围）随访6.9（6.3,7.4）年期间，发生2649例（2.8%）死亡。强度调节了一天中最活跃分钟的积累与死亡风险之间的关系，表达相对于零星积累的中度PA。如果最活跃的分钟数是中等强度，无论持续时间如何，与零星积累相比，连续积累的死亡风险降低一半；如果最活跃的分钟是剧烈的强度，连续发作与持续时间小于5分钟的最低风险相关(例如，3分钟：风险比（HR） = 0.27,(95%可信区间（95%CI）： 0.21-0.34)，而零星积累与持续时间超过5分钟的最低风险相关（HR = 0.11,（95%CI: 0.08-0.15）对于最活跃的20分钟）。结论：降低死亡率的最佳PA模式因强度和持续时间不同而不同。对于中等强度的PA，可以通过优先进行长达20分钟的连续PA来降低死亡风险。然而，对于高强度PA，多次短时间发作(

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来源期刊

Journal of Sport and Health Science SPORT SCIENCES-

CiteScore

18.30

自引率

1.70%

发文量

101

审稿时长

22 weeks

期刊介绍： The Journal of Sport and Health Science (JSHS) is an international, multidisciplinary journal that aims to advance the fields of sport, exercise, physical activity, and health sciences. Published by Elsevier B.V. on behalf of Shanghai University of Sport, JSHS is dedicated to promoting original and impactful research, as well as topical reviews, editorials, opinions, and commentary papers. With a focus on physical and mental health, injury and disease prevention, traditional Chinese exercise, and human performance, JSHS offers a platform for scholars and researchers to share their findings and contribute to the advancement of these fields. Our journal is peer-reviewed, ensuring that all published works meet the highest academic standards. Supported by a carefully selected international editorial board, JSHS upholds impeccable integrity and provides an efficient publication platform. We invite submissions from scholars and researchers worldwide, and we are committed to disseminating insightful and influential research in the field of sport and health science.