LI-RADS: concordance between energy-integrating computed tomography, photon-counting detector computed tomography and magnetic resonance imaging.

IF 3.5 2区 医学 Q2 ONCOLOGY
Lukas Müller, Tobias Jorg, Fabian Stoehr, Jan-Peter Grunz, Dirk Graafen, Moritz C Halfmann, Henner Huflage, Friedrich Foerster, Jens Mittler, Daniel Pinto Dos Santos, Tobias Bäuerle, Roman Kloeckner, Tilman Emrich
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引用次数: 0

Abstract

Background: Photon-counting detector CT (PCD-CT) offers technical advantages over energy-integrating detector CT (EID-CT) for liver imaging. However, it is unclear whether these translate into clinical improvements regarding the classification of suspicious liver lesions using the Liver Imaging Reporting and Data System (LI-RADS). This study compared the intra- and intermodal agreement of EID-CT and PCD-CT with Magnetic resonance imaging (MRI) for liver lesion classification.

Methods: This retrospective study included patients who underwent EID-CT or PCD-CT and MRI within 30 days between 02/2023 and 01/2024. Three board-certified radiologists assessed LI-RADS classification and presence of LI-RADS major features. Fleiss' Kappa and intraclass correlation coefficients (ICC) were used to evaluate rater agreement.

Results: Sixty-eight lesions in 26 patients (mean age 65.0 ± 14.2 years, 19 [73.1%] male) were analyzed. Intramodal inter-rater agreement for LI-RADS classification was 0.88 (0.62-0.88) for EID-CT, 0.90 (0.83-0.94) for PCD-CT, and 0.87 (0.81-0.91) for MRI. Agreement in PCD-CT was substantial for all LI-RADS major features, whereas in EID-CT only for washout. Intermodal agreement between CT and MRI ranged from 0.67 to 0.72. Final intermodal LI-RADS classification agreement was higher for PCD-CT (0.72-0.85) than EID-CT (0.52-0.64).

Conclusions: PCD-CT demonstrated higher intermodal and intramodal agreement for LI-RADS classification and major features than EID-CT. Additionally, PCD-CT shows significantly higher intramodal and inter-rater agreement for LI-RADS classification and greater concordance with MRI compared to EID-CT, reaching substantial to almost perfect agreement. These results suggest a potential benefit of PCD-CT in the management and treatment decision-making of HCC.

LI-RADS:能量积分计算机断层扫描,光子计数检测器计算机断层扫描和磁共振成像之间的一致性。
背景:光子计数检测器CT (PCD-CT)在肝脏成像方面比能量积分检测器CT (EID-CT)具有技术优势。然而,目前尚不清楚这些是否转化为使用肝脏成像报告和数据系统(LI-RADS)对可疑肝脏病变分类的临床改进。本研究比较了EID-CT和PCD-CT与磁共振成像(MRI)对肝脏病变分类的模内和模间一致性。方法:本回顾性研究纳入2023年2月至2024年1月30天内接受EID-CT或PCD-CT和MRI检查的患者。三名委员会认证的放射科医生评估了LI-RADS的分类和LI-RADS主要特征的存在。采用Fleiss’Kappa和类内相关系数(ICC)评价评分一致性。结果:分析了26例患者68个病变,平均年龄(65.0±14.2)岁,男性19例(73.1%)。对LI-RADS分类,EID-CT的模内一致性为0.88 (0.62-0.88),PCD-CT的一致性为0.90 (0.83-0.94),MRI的一致性为0.87(0.81-0.91)。在PCD-CT中,所有LI-RADS的主要特征都是一致的,而在EID-CT中,只有冲洗。CT与MRI的多模态一致性范围为0.67 ~ 0.72。PCD-CT的最终联运LI-RADS分类一致性(0.72-0.85)高于EID-CT(0.52-0.64)。结论:与EID-CT相比,PCD-CT在LI-RADS分类和主要特征方面表现出更高的模态间和模态内一致性。此外,与EID-CT相比,PCD-CT对LI-RADS分类的模内和模间一致性明显更高,与MRI的一致性也更强,几乎完全一致。这些结果表明PCD-CT在HCC的管理和治疗决策中具有潜在的优势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer Imaging
Cancer Imaging ONCOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
CiteScore
7.00
自引率
0.00%
发文量
66
审稿时长
>12 weeks
期刊介绍: Cancer Imaging is an open access, peer-reviewed journal publishing original articles, reviews and editorials written by expert international radiologists working in oncology. The journal encompasses CT, MR, PET, ultrasound, radionuclide and multimodal imaging in all kinds of malignant tumours, plus new developments, techniques and innovations. Topics of interest include: Breast Imaging Chest Complications of treatment Ear, Nose & Throat Gastrointestinal Hepatobiliary & Pancreatic Imaging biomarkers Interventional Lymphoma Measurement of tumour response Molecular functional imaging Musculoskeletal Neuro oncology Nuclear Medicine Paediatric.
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