{"title":"Accurate flow speed measurement through correlation ratios using a mode-selective photonic lantern in optical coherence tomography.","authors":"Raphaël Maltais-Tariant, Rodrigo Itzamna Becerra-Deana, Simon Brais-Brunet, Mathieu Dehaes, Caroline Boudoux","doi":"10.1364/BOE.564589","DOIUrl":null,"url":null,"abstract":"<p><p>A novel method for measuring non-axial flow speed using optical techniques such as optical coherence tomography is introduced. The approach was based on the use of a modally-specific photonic lantern, which permits simultaneous probing of the sample with three distinct coherent spread functions. Transverse flow speed is measured from the ratio between the cross-correlation and autocorrelation of the signals. It achieved a 3 to 5 times higher accuracy than common autocorrelation approaches and measured flows as slow as 0.5 mm/s for an integration time of 1 second. Additionally, the method gives information on the flow's three-dimensional orientation, does not require information about the diffusion coefficient, and is more robust to bias errors such as a gradient in the axial flow velocity.</p>","PeriodicalId":8969,"journal":{"name":"Biomedical optics express","volume":"16 8","pages":"3395-3414"},"PeriodicalIF":3.2000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12339297/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical optics express","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1364/BOE.564589","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
A novel method for measuring non-axial flow speed using optical techniques such as optical coherence tomography is introduced. The approach was based on the use of a modally-specific photonic lantern, which permits simultaneous probing of the sample with three distinct coherent spread functions. Transverse flow speed is measured from the ratio between the cross-correlation and autocorrelation of the signals. It achieved a 3 to 5 times higher accuracy than common autocorrelation approaches and measured flows as slow as 0.5 mm/s for an integration time of 1 second. Additionally, the method gives information on the flow's three-dimensional orientation, does not require information about the diffusion coefficient, and is more robust to bias errors such as a gradient in the axial flow velocity.
期刊介绍:
The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including:
Tissue optics and spectroscopy
Novel microscopies
Optical coherence tomography
Diffuse and fluorescence tomography
Photoacoustic and multimodal imaging
Molecular imaging and therapies
Nanophotonic biosensing
Optical biophysics/photobiology
Microfluidic optical devices
Vision research.