Recent progress in the visible-light-promoted synthesis of phenanthridines

IF 8.9 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Xia Mi , Chaoyang Wang , Jingyu Zhang , Remi Chauvin , Xiuling Cui
{"title":"Recent progress in the visible-light-promoted synthesis of phenanthridines","authors":"Xia Mi ,&nbsp;Chaoyang Wang ,&nbsp;Jingyu Zhang ,&nbsp;Remi Chauvin ,&nbsp;Xiuling Cui","doi":"10.1016/j.cclet.2025.111485","DOIUrl":null,"url":null,"abstract":"<div><div>Phenanthridine is a key structural motif in numerous natural products and biologically active compounds, making it an attractive target for pharmaceuticals and advanced materials. Recently, visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions, paving the way for new applications in synthetic and medicinal chemistry. This review highlights recent progress in the photochemical synthesis of phenanthridines, mainly focusing on various radical acceptors, including 2-isocyanobiaryls, cyanides, vinyl azides and vinyl benzotriazoles.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 11","pages":"Article 111485"},"PeriodicalIF":8.9000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Chemical Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1001841725006680","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Phenanthridine is a key structural motif in numerous natural products and biologically active compounds, making it an attractive target for pharmaceuticals and advanced materials. Recently, visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions, paving the way for new applications in synthetic and medicinal chemistry. This review highlights recent progress in the photochemical synthesis of phenanthridines, mainly focusing on various radical acceptors, including 2-isocyanobiaryls, cyanides, vinyl azides and vinyl benzotriazoles.

Abstract Image

可见光催化菲菲啉合成的最新进展
菲苯胺是许多天然产物和生物活性化合物的关键结构基序,使其成为药物和先进材料的一个有吸引力的靶点。最近,通过自由基过程的可见光诱导环化已经成为在温和和环境友好的条件下构建这样一个核心的强大和可持续的策略,为合成和药物化学的新应用铺平了道路。本文综述了近年来菲并啶类化合物光化学合成的研究进展,重点介绍了各种自由基受体,包括2-异氰基、氰化物、乙烯基叠氮化物和乙烯基苯并三唑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Chinese Chemical Letters
Chinese Chemical Letters 化学-化学综合
CiteScore
14.10
自引率
15.40%
发文量
8969
审稿时长
1.6 months
期刊介绍: Chinese Chemical Letters (CCL) (ISSN 1001-8417) was founded in July 1990. The journal publishes preliminary accounts in the whole field of chemistry, including inorganic chemistry, organic chemistry, analytical chemistry, physical chemistry, polymer chemistry, applied chemistry, etc.Chinese Chemical Letters does not accept articles previously published or scheduled to be published. To verify originality, your article may be checked by the originality detection service CrossCheck.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信