Systematic review and meta-analysis of psychological interventions for depression symptoms in young people with long-term physical health conditions.

IF 2.1 3区心理学 Q2 PSYCHOLOGY, DEVELOPMENTAL

Journal of Pediatric Psychology Pub Date : 2025-07-01 DOI:10.1093/jpepsy/jsaf049

Sarah E D Perzow, Junxiao Hu, Madison Bristol, Elizabeth B Ruzicka, Michelle A Clementi, Elizabeth P Handing, Elizabeth Vargas, Ana M Gutierrez-Colina, Lauren D Gulley, Lauren B Shomaker

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引用次数: 0

Abstract

Objectives: Depression is prevalent, impairing, and detrimental to health. The objective of this systematic review and meta-analysis was to assess the efficacy of psychological interventions for decreasing symptoms of depression among young people with long-term physical health conditions.

Methods: CENTRAL, MEDLINE, PsycINFO, PubMed, clinicaltrials.gov, and WHO ICTRIP were searched through July 1, 2023. Selection criteria were randomized controlled trials of psychological interventions targeting depression symptoms among people ≤29 years diagnosed with long-term physical health conditions. Risk of bias was assessed using the Cochrane RoB version 2 tool. Outcome data were analyzed using fixed-effects models. Pooled standardized mean difference (SMD) between experimental and control was calculated using an inverse variance approach with a linear model. Heterogeneity was assessed by χ2 test on Cochran's Q statistic and quantified with I2 statistic.

Results: Results included six trials (N = 376) of 11- to 18-year-olds (Mfemale=80%), recruited from pediatric clinics in the United States. Two of six eligible studies had an inclusion criterion related to elevated depression symptoms; the remainder included youth with heterogeneous depression levels. Psychological interventions were more efficacious than controls for reducing depression symptoms and functional disability. Pooled SMD for depression symptoms was -.30 (-.51, -.10), with a significant overall effect (Z = 2.92, p = .004). Pooled SMD for functional disability was -.35 (-.66, -.05), with a significant overall effect (Z = 2.28, p = .02). Moderate study heterogeneity was noted in two study outcomes.

Conclusions: Psychological interventions reduce depression symptoms and functional disability among youth with long-term physical health conditions. Research is needed to elucidate participant/trial characteristics contributing to outcomes.

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心理干预对长期身体健康状况的年轻人抑郁症状的系统回顾和荟萃分析。

目的：抑郁症很普遍，对健康有害。本系统综述和荟萃分析的目的是评估心理干预对减少长期身体健康状况的年轻人抑郁症状的疗效。方法：检索截止到2023年7月1日的CENTRAL、MEDLINE、PsycINFO、PubMed、clinicaltrials.gov和WHO ICTRIP。选择标准是针对诊断为长期身体健康状况的≤29岁人群的抑郁症状进行心理干预的随机对照试验。使用Cochrane RoB第2版工具评估偏倚风险。结果数据采用固定效应模型进行分析。采用线性模型逆方差法计算实验与对照间的混合标准化平均差（SMD）。异质性采用Cochran’s Q统计量χ2检验，I2统计量量化。结果：结果包括6项试验（N = 376），从美国儿科诊所招募11至18岁的儿童（女性=80%）。六项符合条件的研究中有两项纳入标准与抑郁症状升高有关；其余包括患有不同抑郁水平的青少年。心理干预在减轻抑郁症状和功能残疾方面比对照组更有效。抑郁症状的综合SMD为- 0.30(-。51, - 0.10)，总体效果显著（Z = 2.92, p = 0.004）。功能性残疾的综合SMD为- 0.35(-。66, - 0.05)，总体效果显著（Z = 2.28, p = 0.02）。两项研究结果均存在中度异质性。结论：心理干预可减少长期身体健康状况青少年的抑郁症状和功能障碍。需要研究来阐明对结果有贡献的参与者/试验特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pediatric Psychology PSYCHOLOGY, DEVELOPMENTAL-

CiteScore

6.00

自引率

11.10%

发文量

期刊介绍： The Journal of Pediatric Psychology is the official journal of the Society of Pediatric Psychology, Division 54 of the American Psychological Association. The Journal of Pediatric Psychology publishes articles related to theory, research, and professional practice in pediatric psychology. Pediatric psychology is an integrated field of science and practice in which the principles of psychology are applied within the context of pediatric health. The field aims to promote the health and development of children, adolescents, and their families through use of evidence-based methods.