Clinical outcomes of internal fixation orthopaedic surgery in humanitarian settings: a retrospective cohort study at the Médecins Sans Frontières (MSF) trauma centre in Aden, Yemen.

IF 2.6 3区 医学 Q2 ORTHOPEDICS
International Orthopaedics Pub Date : 2025-10-01 Epub Date: 2025-08-13 DOI:10.1007/s00264-025-06616-y
Rami Malaeb, Taha Hussain, Fares Ayyash, Abdulsalam Abdullah, Hameed S Ahmed, Khaled Abdulrahman, Adel Al Haj, Hesham Bin Shahna, Evgenia Zelikova, Ibrahim Hassanin, Elisabeth Poulet, Patrick Herard, Rasheed Fakhri
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引用次数: 0

Abstract

Purpose: The Aden Trauma Centre in Yemen, supported by Médecins Sans Frontières (MSF), introduced internal fixation (IF) procedures to address the high burden of fractures as a result of road traffic accidents and conflict-related injuries. This study aimed to describe the clinical characteristics of patients undergoing IF, evaluate their complication and healing outcomes, and explore factors influencing postoperative results.

Methods: A retrospective cohort design was employed, including all patients who underwent internal fixation-using SIGN nails or plates/screws-between January and December 2022. Demographic information, fracture characteristics, surgical techniques, and postoperative outcomes were analyzed. Cox proportional hazards models were used to identify key predictors of complications and bone healing.

Results: A total of 177 patients (208 fractures) were included. The overall complication rate was 14.4%. Open fractures and comorbidities were significant predictors of complications, while type of implant (SIGN nail vs. plate/screws) did not affect complication risk. Around three-quarters of fractures achieved radiographic healing at a median of five to six months. Infection and other complications emerged as major risk factors for delayed or impaired union. About a quarter of patients defaulted from care, potentially underestimating late complications and nonunion rates.

Conclusion: Findings indicate that IF is feasible and effective in this high-need, low-resource context, demonstrating complication rates in line with global estimates. Open fractures, comorbidities, and limited follow-up infrastructure remain the main challenges to optimizing outcomes in such contexts.

人道主义环境下内固定矫形手术的临床结果:也门亚丁无国界医生创伤中心的回顾性队列研究。
目的:也门的亚丁创伤中心在无国界医生组织(MSF)的支持下,采用了内固定程序,以解决道路交通事故和冲突相关伤害造成的严重骨折负担。本研究旨在描述IF患者的临床特点,评估其并发症和愈合情况,探讨影响术后结果的因素。方法:采用回顾性队列设计,包括2022年1月至12月期间使用SIGN钉子或钢板/螺钉进行内固定的所有患者。分析了人口统计信息、骨折特征、手术技术和术后结果。Cox比例风险模型用于确定并发症和骨愈合的关键预测因素。结果:共纳入177例患者(208例骨折)。总并发症发生率为14.4%。开放性骨折和合并症是并发症的重要预测因素,而植入物类型(SIGN钉vs.钢板/螺钉)不影响并发症风险。大约四分之三的骨折在5到6个月的中位时间内实现了x线片愈合。感染和其他并发症是延迟或损害愈合的主要危险因素。大约四分之一的患者不接受治疗,可能低估了晚期并发症和不愈合率。结论:研究结果表明,在这种高需求、低资源的情况下,IF是可行和有效的,其并发症发生率与全球估计相符。开放性骨折、合并症和随访基础设施有限仍然是优化此类情况下预后的主要挑战。
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来源期刊
International Orthopaedics
International Orthopaedics 医学-整形外科
CiteScore
5.50
自引率
7.40%
发文量
360
审稿时长
1 months
期刊介绍: International Orthopaedics, the Official Journal of the Société Internationale de Chirurgie Orthopédique et de Traumatologie (SICOT) , publishes original papers from all over the world. The articles deal with clinical orthopaedic surgery or basic research directly connected with orthopaedic surgery. International Orthopaedics will also link all the members of SICOT by means of an insert that will be concerned with SICOT matters. Finally, it is expected that news and information regarding all aspects of orthopaedic surgery, including meetings, panels, instructional courses, etc. will be brought to the attention of the readers. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted. Reports of animal experiments must state that the "Principles of laboratory animal care" (NIH publication No. 85-23, revised 1985) were followed, as well as specific national laws (e.g. the current version of the German Law on the Protection of Animals) where applicable. The editors reserve the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or for failure to fulfil the above-mentioned requirements.
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