Cataract Surgery in Patients With Scleritis in the United States: An IRIS Registry (Intelligent Research in Sight) Analysis.

IF 2.1 3区医学 Q2 OPHTHALMOLOGY

Cornea Pub Date : 2025-08-13 DOI:10.1097/ICO.0000000000003949

Karen R Armbrust, Laura J Kopplin

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Abstract

Purpose: To evaluate outcomes of and risk factors for cataract surgery in patients with scleritis.

Methods: This retrospective cohort study evaluated demographic and ocular features of a surgical cohort of IRIS Registry (Intelligent Research in Sight) patients with scleritis undergoing cataract surgery between 2013 and 2019. Multiple logistic regression was used to identify factors associated with poor postoperative best visual acuity (BVA) in the surgical cohort and to identify risk factors for undergoing cataract surgery by comparing the surgical cohort with a nonsurgical scleritis cohort.

Results: A total of 6716 eyes of 5618 patients with a preexisting scleritis diagnosis underwent cataract surgery. Average BVA improved by approximately 3 Snellen lines: mean ± SD BVA was 0.39 ± 0.43 logMAR preoperatively versus 0.12 ± 0.27 logMAR postoperatively (P < 0.001). Postoperative complication rates were 5% for cystoid macular edema (CME), 2% for retinal detachment, and 2% for corneal edema. Preoperative CME [adjusted odds ratio (aOR) = 2.78, 95% confidence interval (CI) = 1.56-4.86] and poorer preoperative BVA (aOR = 9.10, 95% CI = 5.99-14.30) were associated with postoperative BVA >0.3 logMAR. After adjusting for age and bilaterality, female sex (aOR = 1.15, 95% CI = 1.08-1.22) and smoking (aOR = 1.63, 95% CI = 1.49-1.77) were risk factors for cataract surgery.

Conclusions: Substantial visual improvement occurs after cataract surgery in eyes with scleritis, although close observation for CME, retinal detachment, and corneal edema is warranted. Female sex and smoking are risk factors for cataract surgery in the setting of scleritis.

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美国巩膜炎患者白内障手术：IRIS注册（视力智能研究）分析。

目的：评价巩膜炎患者白内障手术的预后及危险因素。方法：本回顾性队列研究评估了2013年至2019年IRIS注册（视力智能研究）中接受白内障手术的巩膜炎患者的人口统计学和眼部特征。采用多元logistic回归来确定手术队列中与术后最佳视力（BVA）差相关的因素，并通过比较手术队列与非手术巩膜炎队列来确定接受白内障手术的危险因素。结果：5618例既往存在巩膜炎的患者共6716只眼接受了白内障手术。平均BVA改善约3个Snellen系：术前平均±SD BVA为0.39±0.43 logMAR，而术后平均±SD BVA为0.12±0.27 logMAR （P < 0.001）。膀胱样黄斑水肿（CME）术后并发症发生率为5%，视网膜脱离为2%，角膜水肿为2%。术前CME[调整优势比(aOR) = 2.78, 95%可信区间(CI) = 1.56 ~ 4.86]和较差的术前BVA （aOR = 9.10, 95% CI = 5.99 ~ 14.30）与术后BVA >0.3 logMAR相关。在调整了年龄和双侧因素后，女性（aOR = 1.15, 95% CI = 1.08-1.22）和吸烟（aOR = 1.63, 95% CI = 1.49-1.77）是白内障手术的危险因素。结论：尽管有必要密切观察CME、视网膜脱离和角膜水肿的情况，但患有巩膜炎的白内障手术后视力有明显改善。女性性别和吸烟是巩膜炎患者白内障手术的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cornea 医学-眼科学

CiteScore

5.20

自引率

10.70%

发文量

354

审稿时长

3-6 weeks

期刊介绍： For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references. Sponsored by The Cornea Society which was founded as the Castroviejo Cornea Society in 1975.