Role of lipoic acid and gold nanomaterials and nanoclusters for biomedical and environmental applications

IF 5.7 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Materials Research Bulletin Pub Date : 2025-08-07 DOI:10.1016/j.materresbull.2025.113712

Ankita Doi , Mamta Sahu , Priyanka Sharma , Mainak Ganguly

引用次数: 0

Abstract

Gold nano-colloids have garnered interest because of their distinct optical, size-dependent, and interaction characteristics, particularly lipoic acid (LA)-capped gold nanoparticles (GNPs) and gold nanoclusters. This review focuses on their synthesis techniques that improve solubility, stability, and optical behavior, such as ligand exchange, etching, and self-assembled monolayers (SAM). When compared to other hydrophilic ligands, LA offers benefits. Their great biocompatibility and low cytotoxicity make them appropriate for biological applications such drug administration, wound healing, bioimaging, and antioxidant treatments, according to the review. It also looks at how well they can detect pesticides, heavy metals, and nerve toxins using fluorescence and colorimetric sensing. The review concludes by going over the mechanics of pollution sensing, present constraints, and future possibilities, including uses that are in line with the circular economy.

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硫辛酸和金纳米材料和纳米团簇在生物医学和环境应用中的作用

金纳米胶体由于其独特的光学、尺寸依赖性和相互作用特性而引起了人们的兴趣，特别是硫辛酸（LA）覆盖的金纳米粒子（GNPs）和金纳米团簇。本文综述了近年来提高其溶解度、稳定性和光学性能的合成技术，如配体交换、蚀刻和自组装单层（SAM）。与其他亲水性配体相比，LA具有优势。根据综述，它们具有良好的生物相容性和低细胞毒性，使其适合于生物应用，如给药，伤口愈合，生物成像和抗氧化治疗。它还研究了它们利用荧光和比色感应检测农药、重金属和神经毒素的能力。报告最后回顾了污染传感的机制、目前的限制和未来的可能性，包括符合循环经济的用途。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Materials Research Bulletin 工程技术-材料科学：综合

CiteScore

9.80

自引率

5.60%

发文量

372

审稿时长

42 days

期刊介绍： Materials Research Bulletin is an international journal reporting high-impact research on processing-structure-property relationships in functional materials and nanomaterials with interesting electronic, magnetic, optical, thermal, mechanical or catalytic properties. Papers purely on thermodynamics or theoretical calculations (e.g., density functional theory) do not fall within the scope of the journal unless they also demonstrate a clear link to physical properties. Topics covered include functional materials (e.g., dielectrics, pyroelectrics, piezoelectrics, ferroelectrics, relaxors, thermoelectrics, etc.); electrochemistry and solid-state ionics (e.g., photovoltaics, batteries, sensors, and fuel cells); nanomaterials, graphene, and nanocomposites; luminescence and photocatalysis; crystal-structure and defect-structure analysis; novel electronics; non-crystalline solids; flexible electronics; protein-material interactions; and polymeric ion-exchange membranes.