Exploring explainable machine learning techniques to aid dysphagia risk identification: A feasibility study

IF 2.7 3区 医学 Q2 CRITICAL CARE MEDICINE
Melanie L. McIntyre BHSc SpPath, GradCertClinEd , Yuxi Liu BEng, PhD , Joanne Murray PhD, BAppSc(Speech Pathology), CPSP , Shaowen Qin BEng, MEng, MS(Applied Mathematics), PhD , Timothy Chimunda MBChB, FCICM, AMC, MCC, MACEM , Sebastian H. Doeltgen MSLT, PhD
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引用次数: 0

Abstract

Background

Machine learning offers opportunities to identify complex risk patterns in large data sets. We explored the methodological feasibility, and proof of concept, of applying machine learning techniques to dysphagia (swallowing difficulty) risk identification for adult patients who required endotracheal intubation within an intensive care unit (ICU).

Aim

The aim of this study was to explore the methodological feasibility and proof of concept of developing machine learning models for dysphagia risk identification for adult patients who required endotracheal intubation within an ICU.

Methods

In this cohort study, two large healthcare databases were linked using deterministic logic. All participants received invasive mechanical ventilation in an ICU. Several machine learning model candidates were explored. Insights into the model decision-making have been provided using SHapley Additive exPlanation values.

Results

A total of 59 811 patients from 42 sites were included in the study. The top five most influential factors in determining the presence or absence of dysphagia at a cohort level were duration of mechanical ventilation, age, cardiac admission, neurological admission, and Acute Physiology and Chronic Health Evaluation III score.

Conclusion

There is a promising prospect of machine learning in dynamic dysphagia risk screening, which we propose should be considered for clinical use in the future. The patient-specific influence of each risk factor in determining the presence or absence of dysphagia highlights the importance of determining risk based on the individual patient's unique combination of risk factors, and not on cohort means, as has been done previously.
探索可解释的机器学习技术,以帮助识别吞咽困难的风险:可行性研究
机器学习为识别大型数据集中的复杂风险模式提供了机会。我们探讨了将机器学习技术应用于重症监护病房(ICU)内需要气管插管的成年患者吞咽困难(吞咽困难)风险识别的方法学可行性和概念证明。目的本研究的目的是探索开发机器学习模型的方法可行性和概念的证明,以识别ICU内需要气管插管的成年患者吞咽困难的风险。方法在本队列研究中,使用确定性逻辑将两个大型医疗数据库联系起来。所有参与者在ICU接受有创机械通气。探讨了几种机器学习候选模型。使用SHapley加性解释值提供了对模型决策的见解。结果共纳入42个部位的59 811例患者。在队列水平上决定是否存在吞咽困难的前五个最具影响力的因素是机械通气时间、年龄、心脏住院、神经住院和急性生理和慢性健康评估III评分。结论机器学习在动态吞咽困难风险筛查中具有广阔的应用前景,值得临床推广应用。每个风险因素在确定是否存在吞咽困难方面的患者特异性影响突出了基于个体患者独特的风险因素组合来确定风险的重要性,而不是像以前那样通过队列方法来确定风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Australian Critical Care
Australian Critical Care NURSING-NURSING
CiteScore
4.90
自引率
9.10%
发文量
148
审稿时长
>12 weeks
期刊介绍: Australian Critical Care is the official journal of the Australian College of Critical Care Nurses (ACCCN). It is a bi-monthly peer-reviewed journal, providing clinically relevant research, reviews and articles of interest to the critical care community. Australian Critical Care publishes peer-reviewed scholarly papers that report research findings, research-based reviews, discussion papers and commentaries which are of interest to an international readership of critical care practitioners, educators, administrators and researchers. Interprofessional articles are welcomed.
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