Relationship between fecal egg count, parasite load, and histopathological findings in the pancreas of cattle naturally infected with Eurytrema coelomaticum

IF 1.4 Q3 PARASITOLOGY

Veterinary parasitology, regional studies and reports Pub Date : 2025-08-12 DOI:10.1016/j.vprsr.2025.101325

Andrea Julia Pantiu , Tomás Häberle , Agustín Avellaneda-Cáceres , Leandro Hipólito Olmos , Álvaro Francisco Ruiz , Marcelo Signorini , Juan Francisco Micheloud

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Abstract

Eurytrematosis, a disease caused by Eurytrema spp., primarily affects the pancreas of mammals, including cattle. Although common in Africa, Asia and South America, Eurytrema coelomaticum has recently been detected in Argentina. The present study aimed to evaluate the relationship between parasite load, fecal egg counts (EPG) using two diagnostic techniques (BST and OST), and histopathological lesions in cattle naturally infected with Eurytrema. A total of 120 cattle from an endemic area were selected for the study, with both pancreatic and fecal samples collected for parasitological and histopathological analysis. Histopathological lesions were classified into three grades based on the severity of pancreatic damage. The results demonstrated a significant difference between the parasitic load and the severity of pancreatic lesions (P= 0.001). Both diagnostic techniques demonstrated a significant difference between parasite presence and lesion severity; however, the OST showed higher sensitivity (88 %) and fewer false negatives (12 %) compared to the BST, which exhibited 65 % sensitivity and 35 % false negatives. Histopathological findings revealed more severe lesions, such as fibrosis and interstitial inflammation, in animals with higher parasite loads. These results emphasize the importance of combining reliable diagnostic techniques like OST with histopathological analysis to improve the understanding and management of eurytrematosis in cattle. The findings provide valuable insights into the disease's impact and suggest strategies for controlling its effects on livestock health and productivity.

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粪卵数、寄生虫载量和牛胰腺组织病理学结果之间的关系

Eurytrematosis是一种由Eurytrema引起的疾病，主要影响包括牛在内的哺乳动物的胰腺。虽然常见于非洲、亚洲和南美洲，但最近在阿根廷也发现了Eurytrema coelomaticum。本研究旨在通过两种诊断技术（BST和OST）来评估牛耳鳞病的寄生虫载量、粪卵计数（EPG）与组织病理学病变之间的关系。研究人员从一个流行地区共选取了120头牛，收集了胰腺和粪便样本进行寄生虫学和组织病理学分析。组织病理学病变根据胰腺损伤的严重程度分为三个等级。结果显示寄生负荷和胰腺病变严重程度之间存在显著差异（P= 0.001）。两种诊断技术都显示了寄生虫存在和病变严重程度之间的显著差异；然而，与BST相比，OST表现出更高的灵敏度（88%）和更少的假阴性（12%），BST表现出65%的灵敏度和35%的假阴性。组织病理学结果显示，在寄生虫负荷较高的动物中，更严重的病变，如纤维化和间质性炎症。这些结果强调了将可靠的诊断技术（如OST）与组织病理学分析相结合的重要性，以提高对牛血肿病的认识和管理。这些发现为了解该病的影响提供了有价值的见解，并提出了控制其对牲畜健康和生产力影响的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary parasitology, regional studies and reports Multiple-

CiteScore

2.90

自引率

7.10%

发文量

126

审稿时长

97 days

期刊介绍： Veterinary Parasitology: Regional Studies and Reports focuses on aspects of veterinary parasitology that are of regional concern, which is especially important in this era of climate change and the rapid and often unconstrained travel of people and animals. Relative to regions, this journal will accept papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites within the field of veterinary medicine. Also, case reports will be considered as they add to information related to local disease and its control; such papers must be concise and represent appropriate medical intervention. Papers on veterinary parasitology from wildlife species are acceptable, but only if they relate to the practice of veterinary medicine. Studies on vector-borne bacterial and viral agents are suitable, but only if the paper deals with vector transmission of these organisms to domesticated animals. Studies dealing with parasite control by means of natural products, both in vivo and in vitro, are more suited for one of the many journals that now specialize in papers of this type. However, due to the regional nature of much of this research, submissions may be considered based upon a case being made by the author(s) to the Editor. Circumstances relating to animal experimentation must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences (obtainable from: Executive Secretary C.I.O.M.S., c/o W.H.O., Via Appia, CH-1211 Geneva 27, Switzerland).