{"title":"Increased Incidence of Candida auris Colonization in Early COVID-19 Pandemic, Orange County, California, USA","authors":"Alissa H. Dratch, Mi Le, Matthew Zahn","doi":"10.3201/eid3109.241342","DOIUrl":null,"url":null,"abstract":"<p><em>Candida auris</em> transmission surged in long-term acute-care hospitals (LTACHs) in Orange County, California, USA, during the COVID-19 pandemic. This study describes the effect of COVID-19 on <em>C. auris</em> transmission by estimating the probability of patient colonization in LTACHs across 5 epidemiologic time periods. Patients had the highest probability of developing new skin colonization during the first COVID-19 wave, with a cumulative incidence of 22.5% (95% CI 18.5–26.6) after a 30-day stay. Once the initial COVID-19 waves abated, a reduction in cumulative incidence of <em>C. auris</em> colonization was observed concurrently with persistent high prevalence, indicating that within-facility transmission can be reduced with proper infection prevention and control practices. Admission screenings and point prevalence surveys provided a wealth of data that guided public health recommendations and supported the objectives of both public health professionals and LTACHs for monitoring facility transmission dynamics and guiding decision making.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"7 1","pages":""},"PeriodicalIF":6.6000,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Emerging Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3201/eid3109.241342","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Candida auris transmission surged in long-term acute-care hospitals (LTACHs) in Orange County, California, USA, during the COVID-19 pandemic. This study describes the effect of COVID-19 on C. auris transmission by estimating the probability of patient colonization in LTACHs across 5 epidemiologic time periods. Patients had the highest probability of developing new skin colonization during the first COVID-19 wave, with a cumulative incidence of 22.5% (95% CI 18.5–26.6) after a 30-day stay. Once the initial COVID-19 waves abated, a reduction in cumulative incidence of C. auris colonization was observed concurrently with persistent high prevalence, indicating that within-facility transmission can be reduced with proper infection prevention and control practices. Admission screenings and point prevalence surveys provided a wealth of data that guided public health recommendations and supported the objectives of both public health professionals and LTACHs for monitoring facility transmission dynamics and guiding decision making.
在2019冠状病毒病大流行期间，美国加利福尼亚州奥兰治县长期急诊医院（lachs）的耳念珠菌传播激增。本研究通过估算5个流行病学时期患者在ltahs中定植的概率，描述了COVID-19对auris传播的影响。患者在第一波COVID-19期间出现新皮肤定植的可能性最高，住院30天后累计发病率为22.5% （95% CI 18.5—26.6）。一旦最初的COVID-19波消退，观察到金黄色葡萄球菌定殖的累积发病率下降，同时持续高流行，这表明通过适当的感染预防和控制措施可以减少设施内传播。入院检查和点状流行率调查提供了丰富的数据，可指导公共卫生建议，并支持公共卫生专业人员和ltach监测设施传播动态和指导决策的目标。
期刊介绍：
Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination.
Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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