Microbial Makeover: Skin microbiome reset after stem cell transplantation

IF 18.7 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2025-08-13 DOI:10.1016/j.chom.2025.07.014

John E. Common, Rebecca P. Payne

引用次数: 0

Abstract

Inborn errors of immunity disrupt host-microbe interactions. In this issue of Cell Host & Microbe, Che et al.¹ examine DOCK8-deficient individuals undergoing stem cell transplantation and show that immune reconstitution rebalances the skin microbiome, underscoring the central role of immunity in shaping cutaneous microbial ecology.

查看原文本刊更多论文

微生物改造：干细胞移植后皮肤微生物组重置

先天的免疫错误会破坏宿主与微生物的相互作用。在本期《细胞宿主》杂志中；微生物，Che等人1研究了接受干细胞移植的dock8缺陷个体，发现免疫重建重新平衡了皮肤微生物组，强调了免疫在塑造皮肤微生物生态中的核心作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.