Emily Danson, Ruth Brunsdon, Amanda Lane-Brown, Vincent Oxenham
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引用次数: 0
Abstract
Acquired Brain Injuries (ABIs) cause long-term disruption to young individuals' development. Persistent cognitive fatigue is a commonly reported sequela following pediatric ABI. Currently, there are no evidence-based interventions targeting cognitive fatigue post-ABI amongst pediatric patients. The current systematic review and meta-analysis aimed to review research on the efficacy of pharmacological and non-pharmacological interventions for cognitive fatigue following pediatric ABI. The review searched terms through relevant databases (including Medline, PsychInfo, Embase, Cinahl and Scopus), using specific inclusion criterion. A total of 6,511 articles were identified. Five articles met the inclusion criteria, and three were of excellent quality. These were categorized into behavioural (Gagnon et al., 2016; Gauvin-Lepage et al., 2020; Hypher et al., 2022; Renaud et al., 2020) and pharmacological interventions (Sakellaris et al., 2008). A meta-analysis of the behavioural interventions using random-effects models was conducted and demonstrated a statistically significant effect on reducing cognitive fatigue from both a self-report and caregiver-report perspective. Although not included in the meta-analysis, Sakellaris et al. (2008) findings also demonstrated creatin as an effective pharmacological intervention. The scarcity of available studies impacted the findings, and thus, further investigation is warranted to support specific treatment guidelines.
获得性脑损伤（ABIs）会对青少年的发育造成长期的影响。持续认知疲劳是小儿ABI后常见的后遗症。目前，尚无针对小儿abi后认知疲劳的循证干预措施。当前的系统综述和荟萃分析旨在回顾有关儿童ABI后认知疲劳的药物和非药物干预效果的研究。通过相关数据库（包括Medline、PsychInfo、Embase、Cinahl和Scopus），采用特定的纳入标准对关键词进行检索。共鉴定出6511件物品。5篇文章符合纳入标准，3篇质量优良。这些被归类为行为[Gagnon， I., Grilli， L., Friedman， D., & Iverson， G. L.(2016)]。一项针对从运动相关脑震荡中恢复缓慢的青少年积极康复的初步研究。斯堪的纳维亚体育医学和科学杂志，26(3),299-306；Gauvin-Lepage， J., Friedman， D., Grilli， L., Sufrategui， M., De Matteo， C., Iverson， G. L.和Gagnon， I.（2020）。以运动为基础的积极康复干预对脑震荡后恢复缓慢的青少年的有效性。临床运动医学杂志，30(5),423-432；Hypher， R., Brandt， A. E., Skovlund， E., Skarbo， A. B., Barder， H. E., Andersson， S., Ro， T. B., Risnes， K., Finnanger， T. G., & Stubberud， J.（2022）。元认知策略训练与心理教育对改善获得性脑损伤儿童和青少年的疲劳：一项随机对照试验。神经心理学，36(7),579-596；Renaud等人，2020]和药物干预[Sakellaris， G., Nasis， G., Kotsiou， M., Tamiolaki， M., Charissis， G., & Evangeliou， A.(2008)]。肌酸预防外伤性头痛、头晕、疲劳。一项初步研究。中华儿科杂志，2008,31(1):331 - 334。使用随机效应模型对行为干预进行了荟萃分析，并从自我报告和照顾者报告的角度证明，行为干预在减少认知疲劳方面具有统计学显著效果。虽然没有包括在meta分析中，[Sakellaris， G., Nasis， G., Kotsiou， M., Tamiolaki， M., Charissis， G., and Evangeliou， A.(2008)]。肌酸预防外伤性头痛、头晕、疲劳。一项初步研究。《儿科学报》，国际儿科杂志，97(1)，31-34]研究结果也证明了创造性是有效的药物干预。现有研究的缺乏影响了结果，因此，有必要进一步调查以支持具体的治疗指南。
期刊介绍：
Neuropsychological Rehabilitation publishes human experimental and clinical research related to rehabilitation, recovery of function, and brain plasticity. The journal is aimed at clinicians who wish to inform their practice in the light of the latest scientific research; at researchers in neurorehabilitation; and finally at researchers in cognitive neuroscience and related fields interested in the mechanisms of recovery and rehabilitation. Papers on neuropsychological assessment will be considered, and special topic reviews (2500-5000 words) addressing specific key questions in rehabilitation, recovery and brain plasticity will also be welcomed. The latter will enter a fast-track refereeing process.
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