Min-Tae Kim, Xing Zhen, Se-Hee Choe, Eunsu Jeon, Tae-Don Kim, Sang-Je Park, Jong-Hee Lee
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引用次数: 0
Abstract
Cynomolgus monkey iPSCs were generated from ear fibroblasts, offering a non-invasive and accessible cell source for autologous therapies and preclinical research. These iPSCs demonstrated robust pluripotency and differentiation potential, successfully giving rise to functional macrophages. Validation confirmed chromosomal stability, transgene clearance, and mycoplasma-free status. While this study focuses on establishing a reliable iPSC source, these cells hold promise for generating functional cell types for potential autologous applications in primate models. This platform provides a valuable foundation for advancing regenerative medicine and precision immunotherapy, bridging the gap between in vitro research and future translational studies.
期刊介绍：
Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.
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